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    corn cornetto [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 38786, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cornprovided by FlyBase
    Official Full Name
    cornettoprovided by FlyBase
    Primary source
    FLYBASE:FBgn0259173
    Locus tag
    Dmel_CG42278
    See related
    AllianceGenome:FB:FBgn0259173
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG32386; CG32390; CG42278; CG8621; Corn; Dmel\CG42278
    Old locus tag
    Dmel_CG32386; Dmel_CG32390
    Summary
    Enables microtubule binding activity. Involved in positive regulation of exocytosis. Located in apical part of cell and cell cortex. Part of protein-containing complex. Is expressed in several structures, including antennal anlage; central brain anlage; central brain primordium; epithelial cell; and presumptive embryonic/larval system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See corn in Genome Data Viewer
    Location:
    65E5-65E6; 3-19 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (7142991..7157073, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (7136091..7150173, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene Acyl-CoA binding protein 3 Neighboring gene Acyl-CoA binding protein 2 Neighboring gene melted Neighboring gene uncharacterized protein Neighboring gene Down syndrome cell adhesion molecule 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A modular toolset of phiC31-based fluorescent protein tagging vectors for Drosophila. Luo J, et al. Fly (Austin), 2019 Mar-Dec. PMID 30885036, Free PMC Article
    2. Inscuteable-dependent apical localization of the microtubule-binding protein Cornetto suggests a role in asymmetric cell division. Bulgheresi S, et al. J Cell Sci, 2001 Oct. PMID 11707517
    3. The growth regulators warts/lats and melted interact in a bistable loop to specify opposite fates in Drosophila R8 photoreceptors. Mikeladze-Dvali T, et al. Cell, 2005 Sep 9. PMID 16143107
    4. Drosophila Melted modulates FOXO and TOR activity. Teleman AA, et al. Dev Cell, 2005 Aug. PMID 16054033
    5. Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes. Kwon M, et al. Genes Dev, 2008 Aug 15. PMID 18662975, Free PMC Article

    See all (40) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables microtubule binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in positive regulation of exocytosis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical part of cell IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of protein-containing complex IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    cornetto
    Names
    CG42278-PB
    CG42278-PC
    CG42278-PD
    CG42278-PE
    corn-PB
    corn-PC
    corn-PD
    corn-PE

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      7142991..7157073 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001274567.1 → NP_001261496.1  cornetto, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261496.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PHM1, Q967H1
      Conserved Domains (2) summary
      PHA03247
      Location:92 → 336
      PHA03247; large tegument protein UL36; Provisional
      TIGR02168
      Location:340 → 627
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    2. NM_168193.3 → NP_729220.2  cornetto, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_729220.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IQ73, Q967H1
      Conserved Domains (2) summary
      PHA03247
      Location:92 → 336
      PHA03247; large tegument protein UL36; Provisional
      TIGR02168
      Location:340 → 627
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    3. NM_001274568.1 → NP_001261497.1  cornetto, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001261497.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PBT2, Q967H1
      Conserved Domains (2) summary
      PHA03247
      Location:92 → 336
      PHA03247; large tegument protein UL36; Provisional
      TIGR02168
      Location:340 → 627
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type

    4. NM_079230.3 → NP_523954.2  cornetto, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523954.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q967H1, Q9VS25
      Related
      FBpp0288915
      Conserved Domains (2) summary
      PHA03247
      Location:92 → 336
      PHA03247; large tegument protein UL36; Provisional
      TIGR02168
      Location:340 → 627
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PBT2 M9PBT2
    M9PHM1 M9PHM1
    Q8IQ73 Q8IQ73
    Q960M7 Q960M7
    Q967H1 Q967H1
    Q9VS25 Q9VS25

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