U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    Nol11 nucleolar protein 11 [ Mus musculus (house mouse) ]

    Gene ID: 68979, updated on 9-Dec-2024

    Summary

    Official Symbol
    Nol11provided by MGI
    Official Full Name
    nucleolar protein 11provided by MGI
    Primary source
    MGI:MGI:1916229
    See related
    Ensembl:ENSMUSG00000018433 AllianceGenome:MGI:1916229
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1500002M01Rik
    Summary
    Predicted to be involved in maturation of SSU-rRNA and positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Predicted to be part of t-UTP complex. Predicted to be active in nucleolus. Orthologous to human NOL11 (nucleolar protein 11). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 10.3), whole brain E14.5 (RPKM 8.4) and 27 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nol11 in Genome Data Viewer
    Location:
    11 E1; 11 70.19 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (107057477..107080207, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (107166651..107189381, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1810010H24 gene Neighboring gene STARR-positive B cell enhancer ABC_E9377 Neighboring gene STARR-positive B cell enhancer mm9_chr11:106905708-106906009 Neighboring gene bromodomain PHD finger transcription factor Neighboring gene STARR-positive B cell enhancer ABC_E2373 Neighboring gene STARR-positive B cell enhancer ABC_E5290 Neighboring gene STARR-positive B cell enhancer ABC_E10725 Neighboring gene STARR-seq mESC enhancer starr_30956 Neighboring gene STARR-positive B cell enhancer ABC_E10726 Neighboring gene STARR-seq mESC enhancer starr_30959 Neighboring gene STARR-seq mESC enhancer starr_30962 Neighboring gene predicted gene 11715 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:107050502-107050685 Neighboring gene STARR-seq mESC enhancer starr_30965 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene predicted gene, 39425 Neighboring gene actin, gamma, cytoplasmic 1 pseudogene Neighboring gene phosphatidylinositol transfer protein, cytoplasmic 1 Neighboring gene STARR-positive B cell enhancer ABC_E7084 Neighboring gene STARR-seq mESC enhancer starr_30969 Neighboring gene STARR-positive B cell enhancer mm9_chr11:107194258-107194558 Neighboring gene predicted gene 11716

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in maturation of SSU-rRNA ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in maturation of SSU-rRNA ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of transcription of nucleolar large rRNA by RNA polymerase I ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of t-UTP complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of t-UTP complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001161329.2NP_001154801.1  nucleolar protein 11 isoform 2

      See identical proteins and their annotated locations for NP_001154801.1

      Status: VALIDATED

      Source sequence(s)
      AK076704, AK078524, AL596116
      Consensus CDS
      CCDS48965.1
      UniProtKB/Swiss-Prot
      Q8BJW5
      Related
      ENSMUSP00000102368.2, ENSMUST00000106757.8
      Conserved Domains (1) summary
      pfam08168
      Location:200243
      NUC205; NUC205 domain
    2. NM_001363078.1NP_001350007.1  nucleolar protein 11 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL596116
      Conserved Domains (1) summary
      pfam08168
      Location:131174
      NUC205; NUC205 domain
    3. NM_133702.3NP_598463.2  nucleolar protein 11 isoform 1

      See identical proteins and their annotated locations for NP_598463.2

      Status: VALIDATED

      Source sequence(s)
      AK076704, AK078524, AL596116
      Consensus CDS
      CCDS25566.1
      UniProtKB/Swiss-Prot
      Q8BGJ1, Q8BJW5, Q8R3Q3, Q99KA5
      Related
      ENSMUSP00000018577.8, ENSMUST00000018577.8
      Conserved Domains (1) summary
      pfam08168
      Location:200243
      NUC205; NUC205 domain

    RNA

    1. NR_156439.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL596116

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      107057477..107080207 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)