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    H2ac25 H2A clustered histone 25 [ Mus musculus (house mouse) ]

    Gene ID: 319162, updated on 9-Dec-2024

    Summary

    Official Symbol
    H2ac25provided by MGI
    Official Full Name
    H2A clustered histone 25provided by MGI
    Primary source
    MGI:MGI:2448458
    See related
    Ensembl:ENSMUSG00000078851 AllianceGenome:MGI:2448458
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    H2aw; Hist3h2a
    Summary
    Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. [provided by RefSeq, Aug 2015]
    Orthologs
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    Genomic context

    See H2ac25 in Genome Data Viewer
    Location:
    11 B1.3; 11 36.38 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (58845511..58846018)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (58954685..58955192)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 51864 Neighboring gene STARR-positive B cell enhancer ABC_E3954 Neighboring gene H2B clustered histone 27 Neighboring gene STARR-positive B cell enhancer ABC_E114 Neighboring gene H2B clustered histone 26 Neighboring gene tripartite motif-containing 17 Neighboring gene STARR-positive B cell enhancer ABC_E5230 Neighboring gene STARR-positive B cell enhancer ABC_E6989 Neighboring gene RIKEN cDNA 2310058D17 gene Neighboring gene H3.4 histone, cluster member Neighboring gene STARR-seq mESC enhancer starr_29613 Neighboring gene tripartite motif-containing 11

    Genomic regions, transcripts, and products

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in UV-damage excision repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in UV-damage excision repair ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heterochromatin formation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in nucleosome disassembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in nucleosome disassembly ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of nucleosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
     
    part_of nucleosome ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    histone H2A type 3
    Names
    H2A.W histone
    histone 3, H2a
    histone cluster 3, H2a

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178218.4NP_835736.1  histone H2A type 3

      See identical proteins and their annotated locations for NP_835736.1

      Status: REVIEWED

      Source sequence(s)
      AL662809
      Consensus CDS
      CCDS24755.1
      UniProtKB/Swiss-Prot
      Q8BFU2
      UniProtKB/TrEMBL
      A0AUV1, A2AB79
      Related
      ENSMUSP00000104445.4, ENSMUST00000108817.5
      Conserved Domains (1) summary
      PTZ00017
      Location:1130
      PTZ00017; histone H2A; Provisional

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      58845511..58846018
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)