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    Scarf2 scavenger receptor class F, member 2 [ Mus musculus (house mouse) ]

    Gene ID: 224024, updated on 9-Dec-2024

    Summary

    Official Symbol
    Scarf2provided by MGI
    Official Full Name
    scavenger receptor class F, member 2provided by MGI
    Primary source
    MGI:MGI:1858430
    See related
    Ensembl:ENSMUSG00000012017 AllianceGenome:MGI:1858430
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NSR1; Srec2; Scatf1; SrecII; SREC-II; SRECRP-1
    Summary
    Enables scavenger receptor activity. Acts upstream of or within heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Predicted to be located in membrane. Is expressed in brain; metanephros; skin; thoracic segment skeleton; and trachea. Human ortholog(s) of this gene implicated in Van den Ende-Gupta syndrome. Orthologous to human SCARF2 (scavenger receptor class F member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Broad expression in lung adult (RPKM 105.4), ovary adult (RPKM 99.7) and 17 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Scarf2 in Genome Data Viewer
    Location:
    16 A3; 16 11.03 cM
    Exon count:
    13
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (17615146..17626158)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (17797282..17808294)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene biorientation of chromosomes in cell division 1, pseudogene Neighboring gene kelch-like 22 Neighboring gene VISTA enhancer mm1629 Neighboring gene zinc finger protein 520, pseudogene Neighboring gene STARR-seq mESC enhancer starr_40262 Neighboring gene family with sequence similarity 246 member A

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    scavenger receptor class F member 2
    Names
    scavenger receptor expressed by endothelial cells 2 (acetyl LDL receptor like)
    scavenger receptor type F

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153790.3NP_722485.1  scavenger receptor class F member 2 precursor

      See identical proteins and their annotated locations for NP_722485.1

      Status: VALIDATED

      Source sequence(s)
      AC078895, AF522197, BC059226
      Consensus CDS
      CCDS28010.1
      UniProtKB/Swiss-Prot
      P59222
      UniProtKB/TrEMBL
      Q58A84
      Related
      ENSMUSP00000012161.4, ENSMUST00000012161.5
      Conserved Domains (1) summary
      PRK12798
      Location:715832
      PRK12798; chemotaxis protein; Reviewed

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      17615146..17626158
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159884.1XP_036015777.1  scavenger receptor class F member 2 isoform X1

      Related
      ENSMUST00000231329.2
      Conserved Domains (3) summary
      PHA03247
      Location:683838
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:526836
      PHA03307; transcriptional regulator ICP4; Provisional
      NF033759
      Location:74431
      exchanger_TraA; outer membrane exchange protein TraA
    2. XM_036159886.1XP_036015779.1  scavenger receptor class F member 2 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:457612
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:300610
      PHA03307; transcriptional regulator ICP4; Provisional
      NF033759
      Location:6205
      exchanger_TraA; outer membrane exchange protein TraA
    3. XM_036159885.1XP_036015778.1  scavenger receptor class F member 2 isoform X2

      Conserved Domains (3) summary
      PHA03247
      Location:457612
      PHA03247; large tegument protein UL36; Provisional
      PHA03307
      Location:300610
      PHA03307; transcriptional regulator ICP4; Provisional
      NF033759
      Location:6205
      exchanger_TraA; outer membrane exchange protein TraA