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    Tmem30c transmembrane protein 30C [ Mus musculus (house mouse) ]

    Gene ID: 71027, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Tmem30cprovided by MGI
    Official Full Name
    transmembrane protein 30Cprovided by MGI
    Primary source
    MGI:MGI:1918277
    See related
    Ensembl:ENSMUSG00000022753 AllianceGenome:MGI:1918277
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Cdc50c; 4933401B01Rik; 4933409A18Rik
    Summary
    Predicted to be involved in phospholipid translocation. Predicted to be located in membrane. Predicted to be active in Golgi apparatus; endoplasmic reticulum; and plasma membrane. Orthologous to human TMEM30CP (transmembrane protein 30C, pseudogene). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 17.8) See more
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    Genomic context

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    See Tmem30c in Genome Data Viewer
    Location:
    16 C1.1; 16 34.22 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (57086502..57122185, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (57266139..57301904, complement)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_41078 Neighboring gene STARR-positive B cell enhancer ABC_E8637 Neighboring gene predicted gene, 16892 Neighboring gene TBC1 domain family, member 23 Neighboring gene nitrilase family, member 2 Neighboring gene STARR-positive B cell enhancer ABC_E11617 Neighboring gene STARR-positive B cell enhancer mm9_chr16:57231379-57231680 Neighboring gene STARR-seq mESC enhancer starr_41080 Neighboring gene STARR-seq mESC enhancer starr_41081 Neighboring gene STARR-seq mESC enhancer starr_41082 Neighboring gene STARR-seq mESC enhancer starr_41083 Neighboring gene predicted gene, 26800 Neighboring gene RIKEN cDNA 4921517D16 gene Neighboring gene cms small ribosomal subunit 1 Neighboring gene filamin A interacting protein 1-like Neighboring gene STARR-seq mESC enhancer starr_41085 Neighboring gene STARR-positive B cell enhancer ABC_E11618 Neighboring gene chaperonin containing Tcp1, subunit 8 (theta) pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Characterization and expression of mouse Cdc50c during spermatogenesis. Xu P, et al. Acta Biochim Biophys Sin (Shanghai), 2007 Oct. PMID 17928922
    2. Impaired Spermatogenesis, Muscle, and Erythrocyte Function in U12 Intron Splicing-Defective Zrsr1 Mutant Mice. Horiuchi K, et al. Cell Rep, 2018 Apr 3. PMID 29617656
    3. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in phospholipid translocation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cell cycle control protein 50C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_027651.1 → NP_081927.1  cell cycle control protein 50C

      See identical proteins and their annotated locations for NP_081927.1

      Status: VALIDATED

      Source sequence(s)
      AK016597, AK161475, CT025521
      Consensus CDS
      CCDS49876.1
      UniProtKB/Swiss-Prot
      A9C447, Q9D4D7
      UniProtKB/TrEMBL
      A9C448
      Related
      ENSMUSP00000112989.2, ENSMUST00000119407.8
      Conserved Domains (1) summary
      pfam03381
      Location:53 → 333
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      57086502..57122185 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030249283.2 → XP_030105143.1  cell cycle control protein 50C isoform X3

      Conserved Domains (1) summary
      pfam03381
      Location:14 → 285
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

    2. XM_011246014.4 → XP_011244316.1  cell cycle control protein 50C isoform X1

      See identical proteins and their annotated locations for XP_011244316.1

      UniProtKB/Swiss-Prot
      A9C447, Q9D4D7
      UniProtKB/TrEMBL
      A9C448
      Conserved Domains (1) summary
      pfam03381
      Location:53 → 333
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

    3. XM_017317134.2 → XP_017172623.1  cell cycle control protein 50C isoform X2

      UniProtKB/TrEMBL
      A9C448
      Conserved Domains (1) summary
      pfam03381
      Location:53 → 327
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

    4. XM_011246012.4 → XP_011244314.1  cell cycle control protein 50C isoform X1

      See identical proteins and their annotated locations for XP_011244314.1

      UniProtKB/Swiss-Prot
      A9C447, Q9D4D7
      UniProtKB/TrEMBL
      A9C448
      Conserved Domains (1) summary
      pfam03381
      Location:53 → 333
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family

    5. XM_030249284.2 → XP_030105144.1  cell cycle control protein 50C isoform X4

      Conserved Domains (1) summary
      pfam03381
      Location:1 → 234
      CDC50; LEM3 (ligand-effect modulator 3) family / CDC50 family
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D4D7.2 GenPept UniProtKB/Swiss-Prot:Q9D4D7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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