Thoc3 THO complex subunit 3 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Thoc3provided by RGD
Official Full Name: THO complex subunit 3provided by RGD
Primary source: RGD:1311669
See related: EnsemblRapid:ENSRNOG00000000104 AllianceGenome:RGD:1311669
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to be involved in mRNA export from nucleus. Predicted to be located in chromosome, telomeric region. Predicted to be part of THO complex part of transcription export complex. Orthologous to human THOC3 (THO complex subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in Thymus (RPKM 171.9), Adrenal (RPKM 116.3) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 17p14

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	17	NC_086035.1 (10148281..10157472)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	17	NC_051352.1 (10143184..10152375)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	17	NC_005116.4 (10676943..10686134)

Chromosome 17 - NC_086035.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by RGD

Process	Evidence Code	Pubs
involved_in mRNA export from nucleus	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
part_of THO complex part of transcription export complex	ISO Inferred from Sequence Orthology more info
located_in chromosome, telomeric region	ISO Inferred from Sequence Orthology more info
part_of transcription export complex	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: THO complex subunit 3

Names: THO complex 3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001106059.1 → NP_001099529.1 THO complex subunit 3

See identical proteins and their annotated locations for NP_001099529.1

Status: PROVISIONAL

Source sequence(s)

CH474032

UniProtKB/TrEMBL

A6KB01, B5DEY5, F7EUM8

Related

ENSRNOP00000000116.6, ENSRNOT00000000116.7

Conserved Domains (2) summary

cd00200
Location:49 → 290

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

sd00039
Location:59 → 97

7WD40; WD40 repeat [structural motif]