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    CG10474 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 37211, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG10474provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0034427
    Locus tag
    Dmel_CG10474
    See related
    AllianceGenome:FB:FBgn0034427
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG10474
    Summary
    Predicted to enable N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity. Predicted to be involved in protein deglycosylation. Predicted to be active in lysosome. Human ortholog(s) of this gene implicated in aspartylglucosaminuria and lysosomal storage disease. Orthologous to human AGA (aspartylglucosaminidase). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG10474 in Genome Data Viewer
    Location:
    56C6-56C7; 2-88 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (19285395..19286730, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (15172900..15174235, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Arylalkylamine N-acetyltransferase-like 5 Neighboring gene Arylalkylamine N-acetyltransferase-like 6 Neighboring gene Arylalkylamine N-acetyltransferase-like 4

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Component Evidence Code Pubs
    is_active_in cytoplasm  
    is_active_in lysosome  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG10474-PA
    NP_611404.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      19285395..19286730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_137560.2 → NP_611404.1  uncharacterized protein Dmel_CG10474 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_611404.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A1ZBI7
      Related
      FBpp0085745
      Conserved Domains (1) summary
      cd04513
      Location:1 → 312
      Glycosylasparaginase; Glycosylasparaginase and similar proteins
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