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    MESR3 Misexpression suppressor of ras 3 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35116, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MESR3provided by FlyBase
    Official Full Name
    Misexpression suppressor of ras 3provided by FlyBase
    Primary source
    FLYBASE:FBgn0032694
    Locus tag
    Dmel_CG15162
    See related
    AllianceGenome:FB:FBgn0032694
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15162; Dmel\CG15162
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in several structures, including anlage in statu nascendi; circulatory system primordium; embryonic/larval midgut primordium; endoderm anlage; and head epidermis primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See MESR3 in Genome Data Viewer
    Location:
    36F7-36F9; 2-53 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (18617256..18661776)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (18617256..18661776)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene Ada2a-containing complex component 2 Neighboring gene Intraflagellar transport 46 Neighboring gene Cytochrome P450 310a1 Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A misexpression screen identifies genes that can modulate RAS1 pathway signaling in Drosophila melanogaster. Huang AM, et al. Genetics, 2000 Nov. PMID 11063696, Free PMC Article
    2. The Genetic Architecture of Natural Variation in Recombination Rate in Drosophila melanogaster. Hunter CM, et al. PLoS Genet, 2016 Apr. PMID 27035832, Free PMC Article
    3. Functional neurogenomics of the courtship song of male Drosophila melanogaster. Moran CN, et al. Cortex, 2009 Jan. PMID 19054505
    4. CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN. Rivas GBS, et al. Curr Biol, 2021 Oct 11. PMID 34331859, Free PMC Article
    5. The Trithorax group protein dMLL3/4 instructs the assembly of the zygotic genome at fertilization. Prudêncio P, et al. EMBO Rep, 2018 Aug. PMID 30037897, Free PMC Article

    See all (37) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    misexpression suppressor of ras 3
    Names
    CG15162-PA
    CG15162-PB
    CG15162-PC
    CG15162-PD
    MESR3-PA
    MESR3-PB
    MESR3-PC
    MESR3-PD
    mis-expression suppressor of ras 3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      18617256..18661776
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078873.4 → NP_523597.2  misexpression suppressor of ras 3, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_523597.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ST36, Q9VJ70
      Related
      FBpp0080623

    2. NM_001273612.2 → NP_001260541.1  misexpression suppressor of ras 3, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260541.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9PDC4

    3. NM_001299122.1 → NP_001286051.1  misexpression suppressor of ras 3, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286051.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KJV2

    4. NM_001273613.2 → NP_001260542.1  misexpression suppressor of ras 3, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001260542.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8ST36, Q9VJ70
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9PDC4 M9PDC4
    Q7KJV2 Q7KJV2
    Q9VJ70 Q9VJ70

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