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    CG5321 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 32399, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG5321provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0030575
    Locus tag
    Dmel_CG5321
    See related
    AllianceGenome:FB:FBgn0030575
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-EST:Posey66; Dmel\CG5321; gamma-BBH
    Summary
    Predicted to enable gamma-butyrobetaine dioxygenase activity. Predicted to be involved in carnitine biosynthetic process. Predicted to be active in mitochondrion. Orthologous to human BBOX1 (gamma-butyrobetaine hydroxylase 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See CG5321 in Genome Data Viewer
    Location:
    12F2-12F2; 1-49 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (14679568..14681418)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (14573601..14575451)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene sobremesa Neighboring gene Netrin-A Neighboring gene Netrin-B Neighboring gene uncharacterized protein Neighboring gene hog

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables gamma-butyrobetaine dioxygenase activity  
    enables oxidoreductase activity  
    Component Evidence Code Pubs
    is_active_in mitochondrion  

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG5321-PB
    CG5321-PC
    gamma-ButyroBetaine hydroxylase
    NP_001285244.1
    NP_572967.2

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      14679568..14681418
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_132739.3 → NP_572967.2  uncharacterized protein Dmel_CG5321, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572967.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4S5, Q9VY24
      Conserved Domains (3) summary
      cd00250
      Location:127 → 395
      CAS_like; Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
      TIGR02409
      Location:49 → 405
      carnitine_bodg; gamma-butyrobetaine hydroxylase
      cl01414
      Location:48 → 113
      DUF971; Protein of unknown function (DUF971)
    2. NM_001298315.1 → NP_001285244.1  uncharacterized protein Dmel_CG5321, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001285244.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V4S5, Q9VY24
      Conserved Domains (3) summary
      cd00250
      Location:127 → 395
      CAS_like; Clavaminic acid synthetase (CAS) -like; CAS is a trifunctional Fe(II)/ 2-oxoglutarate (2OG) oxygenase carrying out three reactions in the biosynthesis of clavulanic acid, an inhibitor of class A serine beta-lactamases. In general, Fe(II)-2OG oxygenases ...
      TIGR02409
      Location:49 → 405
      carnitine_bodg; gamma-butyrobetaine hydroxylase
      cl01414
      Location:48 → 113
      DUF971; Protein of unknown function (DUF971)
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