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    TRAPPC3L trafficking protein particle complex subunit 3L [ Homo sapiens (human) ]

    Gene ID: 100128327, updated on 9-Dec-2024

    Summary

    Official Symbol
    TRAPPC3Lprovided by HGNC
    Official Full Name
    trafficking protein particle complex subunit 3Lprovided by HGNC
    Primary source
    HGNC:HGNC:21090
    See related
    Ensembl:ENSG00000173626 MIM:614137; AllianceGenome:HGNC:21090
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    BET3L; bA259P20.2
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport and intra-Golgi vesicle-mediated transport. Part of TRAPP complex. [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in spleen (RPKM 1.6), placenta (RPKM 1.5) and 5 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See TRAPPC3L in Genome Data Viewer
    Location:
    6q22.1
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 6 NC_000006.12 (116494989..116545684, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 6 NC_060930.1 (117678730..117729406, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (116816152..116866847, complement)

    Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24992 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24993 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17495 Neighboring gene CALHM6 antisense RNA 1 Neighboring gene keratin 18 pseudogene 22 Neighboring gene calcium homeostasis modulator family member 6 Neighboring gene OCT4-H3K27ac hESC enhancer GRCh37_chr6:116832513-116833094 Neighboring gene calcium homeostasis modulator family member 5 Neighboring gene MPRA-validated peak6051 silencer Neighboring gene calcium homeostasis modulator family member 4 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24994 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24995 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 17496 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24996 Neighboring gene RWD domain containing 1 Neighboring gene MPRA-validated peak6052 silencer Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24997 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 24998 Neighboring gene uncharacterized LOC124901386 Neighboring gene radial spoke head component 4A

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ11180

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of TRAPP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of TRAPP complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cis-Golgi network membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    trafficking protein particle complex subunit 3-like protein
    Names
    BET3-like protein
    TRAPPC3-like protein
    trafficking protein particle complex 3 like
    trafficking protein particle complex subunit 3 like

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001139444.3NP_001132916.1  trafficking protein particle complex subunit 3-like protein

      See identical proteins and their annotated locations for NP_001132916.1

      Status: VALIDATED

      Source sequence(s)
      AI090359, AI745276, AL121953, AL445224, BE501784, BX280366, DY655209
      Consensus CDS
      CCDS47468.1
      UniProtKB/Swiss-Prot
      Q5T213, Q5T214, Q5T215
      UniProtKB/TrEMBL
      A0A0A0MSL6
      Related
      ENSP00000357591.3, ENST00000368602.4
      Conserved Domains (1) summary
      cd14942
      Location:15170
      TRAPPC3_bet3; Bet3-TRAPPC3 subunit of the TRAPP complex

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000006.12 Reference GRCh38.p14 Primary Assembly

      Range
      116494989..116545684 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060930.1 Alternate T2T-CHM13v2.0

      Range
      117678730..117729406 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)