DUBR DPPA2 upstream binding RNA [Homo sapiens (human)] - Gene

Summary

Official Symbol: DUBRprovided by HGNC
Official Full Name: DPPA2 upstream binding RNAprovided by HGNC
Primary source: HGNC:HGNC:48569
See related: Ensembl:ENSG00000243701 MIM:616619; AllianceGenome:HGNC:48569
Gene type: ncRNA
RefSeq status: VALIDATED
Organism: Homo sapiens
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as: DUM; LINC0883; LINC00883
Summary: Predicted to act upstream of or within negative regulation of gene expression via chromosomal CpG island methylation; negative regulation of transcription by RNA polymerase II; and positive regulation of myoblast differentiation. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
Expression: Broad expression in ovary (RPKM 6.4), testis (RPKM 4.8) and 22 other tissues See more
Orthologs: mouse all
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Genomic context

Location:: 3q13.12

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCh38.p14 (GCF_000001405.40)	3	NC_000003.12 (107240692..107326964)
RS_2024_08	current	T2T-CHM13v2.0 (GCF_009914755.1)	3	NC_060927.1 (109960376..110046666)
RS_2024_09	previous assembly	GRCh37.p13 (GCF_000001405.25)	3	NC_000003.11 (106959539..107045811)

Chromosome 3 - NC_000003.12 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Linc00883 affects colorectal cancer through miR-577/FKBP14 axis: a novel mechanism for regulating colorectal cancer cell proliferation, invasion, and migration.
Title: Linc00883 affects colorectal cancer through miR-577/FKBP14 axis: a novel mechanism for regulating colorectal cancer cell proliferation, invasion, and migration.
DUBR suppresses migration and invasion of human lung adenocarcinoma cells via ZBTB11-mediated inhibition of oxidative phosphorylation.
Title: DUBR suppresses migration and invasion of human lung adenocarcinoma cells via ZBTB11-mediated inhibition of oxidative phosphorylation.

Submit: New GeneRIF Correction

Phenotypes

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Review eQTL and phenotype association data in this region using PheGenI

Variation

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See variants in ClinVar

See studies and variants in dbVar

See Variation Viewer (GRCh37.p13)

See Variation Viewer (GRCh38)

General gene information

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Markers

D3S3982 (e-PCR)
- UniSTS:27230

SHGC-77172 (e-PCR)
- UniSTS:39330

D3S3045 (e-PCR), detects polymorphism
- UniSTS:8620

RH65921 (e-PCR)
- UniSTS:14508

RH102640 (e-PCR)
- UniSTS:96974

RH48614 (e-PCR)
- UniSTS:75005

Other Names

long intergenic non-protein coding RNA 883

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

NR_028301.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (1) represents the longer transcript.

Source sequence(s)

AC074043, BC039550, BU618315, DA339707

Related

ENST00000466734.6
NR_028302.1 RNA Sequence

Status: VALIDATED

Description

Transcript Variant: This variant (2) uses the same first exon as variant 1, but has a distinct 3' splice pattern.

Source sequence(s)

AC063944, AK309100

Related

ENST00000490441.1