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    Rpl35 ribosomal protein L35 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 296709, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rpl35provided by RGD
    Official Full Name
    ribosomal protein L35provided by RGD
    Primary source
    RGD:1303007
    See related
    EnsemblRapid:ENSRNOG00000014272 AllianceGenome:RGD:1303007
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Enables ribonucleoprotein complex binding activity. Involved in cellular response to UV-B. Part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in Diamond-Blackfan anemia 19. Orthologous to human RPL35 (ribosomal protein L35). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Spleen (RPKM 4951.6), Thymus (RPKM 4147.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Rpl35 in Genome Data Viewer
    Location:
    3q12
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 3 NC_086021.1 (43162960..43166485, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 3 NC_051338.1 (22753255..22756217, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 3 NC_005102.4 (23294813..23297774, complement)

    Chromosome 3 - NC_086021.1Genomic Context describing neighboring genes Neighboring gene olfactomedin-like 2A Neighboring gene golgin A2 like 2 Neighboring gene small nucleolar RNA SNORA79 Neighboring gene WD repeat domain 38 Neighboring gene actin related protein 2/3 complex, subunit 5-like Neighboring gene golgin A1 Neighboring gene suppressor of cancer cell invasion like 1 Neighboring gene suppressor of cancer cell invasion

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Pathways from PubChem

    General gene information

    Clone Names

    • MGC72958

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ribonucleoprotein complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
     
    enables structural constituent of ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic side of rough endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of cytosolic large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of cytosolic large ribosomal subunit IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of cytosolic large ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
     
    part_of cytosolic large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosolic ribosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein uL29
    Names
    60S ribosomal protein L35

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212511.2NP_997676.1  large ribosomal subunit protein uL29

      See identical proteins and their annotated locations for NP_997676.1

      Status: PROVISIONAL

      Source sequence(s)
      BC058499
      UniProtKB/Swiss-Prot
      P17078
      UniProtKB/TrEMBL
      A0A8L2UJE8, A6JEV9
      Related
      ENSRNOP00000019162.7, ENSRNOT00000019162.8
      Conserved Domains (1) summary
      pfam00831
      Location:863
      Ribosomal_L29; Ribosomal L29 protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086021.1 Reference GRCr8

      Range
      43162960..43166485 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_063283528.1XP_063139598.1  large ribosomal subunit protein uL29 isoform X1

      UniProtKB/TrEMBL
      A0A8I5Y7I3