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    Anapc13 anaphase promoting complex subunit 13 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 685029, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Anapc13provided by RGD
    Official Full Name
    anaphase promoting complex subunit 13provided by RGD
    Primary source
    RGD:1583270
    See related
    EnsemblRapid:ENSRNOG00000008459 AllianceGenome:RGD:1583270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to be involved in anaphase-promoting complex-dependent catabolic process and protein polyubiquitination. Predicted to be part of anaphase-promoting complex. Orthologous to human ANAPC13 (anaphase promoting complex subunit 13). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in Kidney (RPKM 96.9), Heart (RPKM 96.2) and 9 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See Anapc13 in Genome Data Viewer
    Location:
    8q32
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (112084405..112092821)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (103205520..103213936)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (111107358..111115774)

    Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene kyphoscoliosis peptidase Neighboring gene ribosomal protein L27, pseudogene 3 Neighboring gene centrosomal protein 63 Neighboring gene uncharacterized LOC134480096 Neighboring gene angiomotin like 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

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    Related articles in PubMed

    1. Mechanism of ubiquitin-chain formation by the human anaphase-promoting complex. Jin L, et al. Cell, 2008 May 16. PMID 18485873, Free PMC Article
    2. Localization of the coactivator Cdh1 and the cullin subunit Apc2 in a cryo-electron microscopy model of vertebrate APC/C. Dube P, et al. Mol Cell, 2005 Dec 22. PMID 16364912
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RGD

    Process Evidence Code Pubs
    involved_in anaphase-promoting complex-dependent catabolic process ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein K11-linked ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein K11-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein K48-linked ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein branched polyubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    part_of anaphase-promoting complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of anaphase-promoting complex ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    anaphase-promoting complex subunit 13

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001173983.3 → NP_001167454.1  anaphase-promoting complex subunit 13

      See identical proteins and their annotated locations for NP_001167454.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000008
      UniProtKB/TrEMBL
      A6I2H8, D4A427
      Related
      ENSRNOP00000011203.2, ENSRNOT00000011203.6
      Conserved Domains (1) summary
      pfam05839
      Location:1 → 74
      Apc13p; Apc13p protein

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086026.1 Reference GRCr8

      Range
      112084405..112092821
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006243681.5 → XP_006243743.1  anaphase-promoting complex subunit 13 isoform X1

      See identical proteins and their annotated locations for XP_006243743.1

      UniProtKB/TrEMBL
      A6I2H8, D4A427
      Conserved Domains (1) summary
      pfam05839
      Location:1 → 74
      Apc13p; Apc13p protein

    2. XM_039082157.2 → XP_038938085.1  anaphase-promoting complex subunit 13 isoform X1

      UniProtKB/TrEMBL
      A6I2H8, D4A427
      Conserved Domains (1) summary
      pfam05839
      Location:1 → 74
      Apc13p; Apc13p protein
    Nucleotide Protein Strain
    Heading Accession and Version

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