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    F57H12.5 Tyrosine-protein phosphatase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 177592, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F57H12.5
    Official Full Name
    Tyrosine-protein phosphatase domain-containing protein
    Primary source
    WormBase:WBGene00019020
    Locus tag
    CELE_F57H12.5
    See related
    AllianceGenome:WB:WBGene00019020
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein tyrosine phosphatase activity. Predicted to be involved in protein dephosphorylation. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F57H12.5 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (7967306..7969600)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene PCI domain-containing protein Neighboring gene Homeobox protein ceh-19 Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Piwi domain-containing protein Neighboring gene DUF148 domain-containing protein Neighboring gene Onchocerca Related Antigen family

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables protein tyrosine phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein dephosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Tyrosine-protein phosphatase domain-containing protein
    NP_001294193.1
    • Confirmed by transcript evidence
    NP_501331.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      7967306..7969600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068930.5 → NP_501331.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501331.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45095
      Conserved Domains (2) summary
      smart00194
      Location:220 → 500
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cl21483
      Location:255 → 498
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    2. NM_001307264.2 → NP_001294193.1  Tyrosine-protein phosphatase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001294193.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      W6SBI6
      Conserved Domains (2) summary
      smart00194
      Location:220 → 477
      PTPc; Protein tyrosine phosphatase, catalytic domain
      cl21483
      Location:255 → 475
      PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...

    RNA

    1. NR_131579.1 RNA Sequence

      Status: REVIEWED

    Nucleotide Protein
    Heading Accession and Version

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