lmtr-2 Ragulator complex protein LAMTOR2 homolog [Caenorhabditis elegans] - Gene

Summary

Official Symbol: lmtr-2
Official Full Name: Ragulator complex protein LAMTOR2 homolog
Primary source: WormBase:WBGene00022402
Locus tag: CELE_Y97E10AR.7
See related: AllianceGenome:WB:WBGene00022402
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to contribute to guanyl-nucleotide exchange factor activity and molecular adaptor activity. Predicted to be involved in several processes, including cellular response to amino acid stimulus; positive regulation of TOR signaling; and regulation of cell growth. Predicted to be part of Ragulator complex. Is expressed in hypodermis and nervous system. Orthologous to human LAMTOR2 (late endosomal/lysosomal adaptor, MAPK and MTOR activator 2). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

Function	Evidence Code	Pubs
enables guanyl-nucleotide exchange factor activity	IEA Inferred from Electronic Annotation more info
contributes_to guanyl-nucleotide exchange factor activity	ISS Inferred from Sequence or Structural Similarity more info
enables molecular adaptor activity	IEA Inferred from Electronic Annotation more info
contributes_to molecular adaptor activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in cellular response to amino acid stimulus	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to amino acid stimulus	ISS Inferred from Sequence or Structural Similarity more info
involved_in positive regulation of TOR signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of TOR signaling	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of TOR signaling	ISS Inferred from Sequence or Structural Similarity more info
involved_in protein localization	ISS Inferred from Sequence or Structural Similarity more info
involved_in regulation of cell growth	ISS Inferred from Sequence or Structural Similarity more info

Component	Evidence Code	Pubs
part_of Ragulator complex	IBA Inferred from Biological aspect of Ancestor more info

NP_505061.1

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