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    zipt-1 Zrt (ZRT), Irt- (IRT-) like Protein Transporter [ Caenorhabditis elegans ]

    Gene ID: 173376, updated on 9-Dec-2024

    Summary

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    Official Symbol
    zipt-1
    Official Full Name
    Zrt (ZRT), Irt- (IRT-) like Protein Transporter
    Primary source
    WormBase:WBGene00009286
    Locus tag
    CELE_F31C3.4
    See related
    AllianceGenome:WB:WBGene00009286
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable zinc ion transmembrane transporter activity. Predicted to be involved in zinc ion transmembrane transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to several human genes including SLC39A1 (solute carrier family 39 member 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See zipt-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    4
    Sequence:
    Chromosome: I; NC_003279.8 (15050797..15052420, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene PAP-associated domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase 5 Neighboring gene FMP27/BLTP2/Hobbit GFWDK motif-containing RBG unit domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein kinase domain-containing protein Neighboring gene putative DNA replication complex GINS protein PSF2 Neighboring gene rRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. RNA targets and specificity of Staufen, a double-stranded RNA-binding protein in Caenorhabditis elegans. LeGendre JB, et al. J Biol Chem, 2013 Jan 25. PMID 23195953, Free PMC Article
    2. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables metal ion transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in metal ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in zinc ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in zinc ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Zrt (ZRT), Irt- (IRT-) like Protein Transporter
    NP_493626.1
    • Product from WormBase gene class zipt;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      15050797..15052420 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061225.7 → NP_493626.1  Zrt (ZRT), Irt- (IRT-) like Protein Transporter [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493626.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62192
      Conserved Domains (1) summary
      pfam02535
      Location:32 → 308
      Zip; ZIP Zinc transporter
    Nucleotide Protein
    Heading Accession and Version

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