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    calf-1 CAlcium channel Localization Factor [ Caenorhabditis elegans ]

    Gene ID: 180342, updated on 9-Dec-2024

    Summary

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    Official Symbol
    calf-1
    Official Full Name
    CAlcium channel Localization Factor
    Primary source
    WormBase:WBGene00007119
    Locus tag
    CELE_B0250.2
    See related
    AllianceGenome:WB:WBGene00007119
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in several processes, including determination of left/right asymmetry in nervous system; protein exit from endoplasmic reticulum; and protein localization to synapse. Located in endoplasmic reticulum membrane. Is expressed in neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See calf-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    5
    Sequence:
    Chromosome: V; NC_003283.11 (20476747..20479089, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene DUF4258 domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Large ribosomal subunit protein uL2

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Calcium: an insignificant thing. Frøkjaer-Jensen C, et al. Nat Neurosci, 2009 Oct. PMID 19783977, Free PMC Article
    2. Excitatory motor neurons are local oscillators for backward locomotion. Gao S, et al. Elife, 2018 Jan 23. PMID 29360035, Free PMC Article
    3. Active Zone Trafficking of CaV2/UNC-2 Channels Is Independent of β/CCB-1 and α2δ/UNC-36 Subunits. Oh KH, et al. J Neurosci, 2023 Jul 12. PMID 37160370, Free PMC Article
    4. Presynaptic CaV2 calcium channel traffic requires CALF-1 and the alpha(2)delta subunit UNC-36. Saheki Y, et al. Nat Neurosci, 2009 Oct. PMID 19718034, Free PMC Article
    5. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in determination of left/right asymmetry in nervous system IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of locomotion IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein exit from endoplasmic reticulum IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in protein localization to synapse IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    CAlcium channel Localization Factor
    NP_507939.1
    • Product from WormBase gene class calf;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      20476747..20479089 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_075538.8 → NP_507939.1  CAlcium channel Localization Factor [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_507939.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XVF6
    Nucleotide Protein
    Heading Accession and Version

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