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    F58B3.4 NUC153 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 178088, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F58B3.4
    Official Full Name
    NUC153 domain-containing protein
    Primary source
    WormBase:WBGene00010231
    Locus tag
    CELE_F58B3.4
    See related
    AllianceGenome:WB:WBGene00010231
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in rRNA processing. Predicted to be located in nucleolus. Is expressed in intestine and nervous system. Orthologous to human ESF1 (ESF1 nucleolar pre-rRNA processing protein homolog). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F58B3.4 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    6
    Sequence:
    Chromosome: IV; NC_003282.8 (11628757..11631850, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Lysozyme-like protein 5 Neighboring gene LYSozyme Neighboring gene Methionine--tRNA ligase, cytoplasmic;tRNA-binding domain-containing protein Neighboring gene ncRNA Neighboring gene Interferon-related developmental regulator N-terminal domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. FACT Sets a Barrier for Cell Fate Reprogramming in Caenorhabditis elegans and Human Cells. Kolundzic E, et al. Dev Cell, 2018 Sep 10. PMID 30078731, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in rRNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    NUC153 domain-containing protein
    NP_502195.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      11628757..11631850 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069794.6 → NP_502195.3  NUC153 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_502195.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20969
      Conserved Domains (1) summary
      COG5638
      Location:205 → 592
      COG5638; Uncharacterized conserved protein [Function unknown]
    Nucleotide Protein
    Heading Accession and Version

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