nmat-1 Nicotinamide-nucleotide adenylyltransferase [Caenorhabditis elegans] - Gene

Summary

Official Symbol: nmat-1
Official Full Name: Nicotinamide-nucleotide adenylyltransferase
Primary source: WormBase:WBGene00012295
Locus tag: CELE_W06B3.1
See related: AllianceGenome:WB:WBGene00012295
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable nicotinamide-nucleotide adenylyltransferase activity and nicotinate-nucleotide adenylyltransferase activity. Predicted to be involved in NAD biosynthetic process. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 9 and spondyloepiphyseal dysplasia, sensorineural hearing loss, intellectual developmental disorder, and Leber congenital amaurosis. Orthologous to human NMNAT1 (nicotinamide nucleotide adenylyltransferase 1) and NMNAT3 (nicotinamide nucleotide adenylyltransferase 3). [provided by Alliance of Genome Resources, Dec 2024]
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Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

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Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables adenylyltransferase activity	IEA Inferred from Electronic Annotation more info
enables catalytic activity	IEA Inferred from Electronic Annotation more info
enables nicotinamide-nucleotide adenylyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables nicotinamide-nucleotide adenylyltransferase activity	IEA Inferred from Electronic Annotation more info
enables nicotinate-nucleotide adenylyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables nicotinate-nucleotide adenylyltransferase activity	IEA Inferred from Electronic Annotation more info
enables nucleotidyltransferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in NAD biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in NAD biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info
involved_in pyridine nucleotide biosynthetic process	IEA Inferred from Electronic Annotation more info

NP_001379025.1

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