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    F36F2.1 Costars domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172722, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F36F2.1
    Official Full Name
    Costars domain-containing protein
    Primary source
    WormBase:WBGene00009475
    Locus tag
    CELE_F36F2.1
    See related
    AllianceGenome:WB:WBGene00009475
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable actin binding activity. Predicted to be involved in positive regulation of Rho protein signal transduction and positive regulation of transcription by RNA polymerase II. Located in endoplasmic reticulum. Is expressed in pharynx. Orthologous to human ABRA (actin binding Rho activating protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F36F2.1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (9018670..9020304)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene EB domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene Cyclic nucleotide-binding domain-containing protein Neighboring gene AB hydrolase-1 domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables actin binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in positive regulation of Rho protein signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of Rho protein signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum HDA PubMed 
    is_active_in sarcomere IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Costars domain-containing protein
    NP_001129772.1
    • Confirmed by transcript evidence
    NP_492426.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      9018670..9020304
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060025.6 → NP_492426.1  Costars domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492426.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62234
      Conserved Domains (1) summary
      pfam14705
      Location:66 → 141
      Costars

    2. NM_001136300.4 → NP_001129772.1  Costars domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001129772.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      B3WFX8
      Conserved Domains (1) summary
      pfam14705
      Location:49 → 124
      Costars
    Nucleotide Protein
    Heading Accession and Version

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