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    pigc-1 Phosphatidylinositol N-acetylglucosaminyltransferase subunit C [ Caenorhabditis elegans ]

    Gene ID: 177765, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pigc-1
    Official Full Name
    Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
    Primary source
    WormBase:WBGene00011860
    Locus tag
    CELE_T20D3.8
    See related
    AllianceGenome:WB:WBGene00011860
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable glycosyltransferase activity. Predicted to be involved in GPI anchor biosynthetic process. Located in nucleus. Human ortholog(s) of this gene implicated in glycosylphosphatidylinositol biosynthesis defect 16. Orthologous to human PIGC (phosphatidylinositol glycan anchor biosynthesis class C). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pigc-1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    5
    Sequence:
    Chromosome: IV; NC_003282.8 (9341964..9343152, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene HIG1 domain-containing protein Neighboring gene Vacuolar protein sorting-associated protein 26 Neighboring gene Piezo-type mechanosensitive ion channel component 1 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Phosphatidylinositol N-acetylglucosaminyltransferase subunit C
    NP_501645.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      9341964..9343152 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_069244.4 → NP_501645.1  Phosphatidylinositol N-acetylglucosaminyltransferase subunit C [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_501645.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01259
      Conserved Domains (1) summary
      pfam06432
      Location:7 → 273
      GPI2; Phosphatidylinositol N-acetylglucosaminyltransferase
    Nucleotide Protein
    Heading Accession and Version

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