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    F45F2.9 5'-deoxynucleotidase HDDC2 [ Caenorhabditis elegans ]

    Gene ID: 185809, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F45F2.9
    Official Full Name
    5'-deoxynucleotidase HDDC2
    Primary source
    WormBase:WBGene00018481
    Locus tag
    CELE_F45F2.9
    See related
    AllianceGenome:WB:WBGene00018481
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable 5'-deoxynucleotidase activity. Is expressed in intestine; nervous system; and rectal gland cell. Orthologous to human HDDC2 (HD domain containing 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F45F2.9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (8512690..8513461, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Peroxidasin homolog pxn-1 Neighboring gene WEB family protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene ANK_REP_REGION domain-containing protein Neighboring gene Protein kinase domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    2. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    3. Empirically controlled mapping of the Caenorhabditis elegans protein-protein interactome network. Simonis N, et al. Nat Methods, 2009 Jan. PMID 19123269, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables 5'-deoxynucleotidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 5'-deoxynucleotidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    5'-deoxynucleotidase HDDC2
    NP_001256098.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      8512690..8513461 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001269169.4 → NP_001256098.1  5'-deoxynucleotidase HDDC2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256098.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E1B6Q7
      Conserved Domains (1) summary
      pfam13023
      Location:13 → 164
      HD_3; HD domain
    Nucleotide Protein
    Heading Accession and Version

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