U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    prp-38 Pre-mRNA-splicing factor 38 [ Caenorhabditis elegans ]

    Gene ID: 179499, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    prp-38
    Official Full Name
    Pre-mRNA-splicing factor 38
    Primary source
    WormBase:WBGene00008380
    Locus tag
    CELE_D1054.14
    See related
    AllianceGenome:WB:WBGene00008380
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be part of precatalytic spliceosome. Orthologous to human PRPF38A (pre-mRNA processing factor 38A). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See prp-38 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (10804721..10806034, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene O-phosphoseryl-tRNA(Sec) selenium transferase Neighboring gene WD_REPEATS_REGION domain-containing protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The ubiquitin-like protein Hub1/UBL-5 functions in pre-mRNA splicing in Caenorhabditis elegans. Kolathur KK, et al. FEBS Lett, 2023 Feb. PMID 36480405, Free PMC Article
    2. Caenorhabditis elegans cisRED: a catalogue of conserved genomic elements. Sleumer MC, et al. Nucleic Acids Res, 2009 Mar. PMID 19151087, Free PMC Article
    3. The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. Ma L, et al. PLoS Genet, 2012. PMID 22829783, Free PMC Article
    4. Sm protein down-regulation leads to defects in nuclear pore complex disassembly and distribution in C. elegans embryos. Joseph-Strauss D, et al. Dev Biol, 2012 May 15. PMID 22426005, Free PMC Article
    5. Lifespan regulation by evolutionarily conserved genes essential for viability. Curran SP, et al. PLoS Genet, 2007 Apr 6. PMID 17411345, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Pre-mRNA-splicing factor 38
    NP_505762.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10804721..10806034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073361.6 → NP_505762.1  Pre-mRNA-splicing factor 38 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505762.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q18942
      Conserved Domains (1) summary
      pfam03371
      Location:10 → 172
      PRP38; PRP38 family
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools