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    • Showing Current items.

    tag-340 START domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 175655, updated on 9-Dec-2024

    Summary

    Official Symbol
    tag-340
    Official Full Name
    START domain-containing protein
    Primary source
    WormBase:WBGene00017826
    Locus tag
    CELE_F26F4.4
    See related
    AllianceGenome:WB:WBGene00017826
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in vesicle tethering to endoplasmic reticulum. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum-endosome membrane contact site and late endosome membrane. Predicted to colocalize with endoplasmic reticulum membrane. Orthologous to several human genes including STARD3 (StAR related lipid transfer domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See tag-340 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    9
    Sequence:
    Chromosome: III; NC_003281.10 (4900508..4903170)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene RING-type E3 ubiquitin transferase Neighboring gene ncRNA Neighboring gene Mediator of RNA polymerase II transcription subunit 21 Neighboring gene C2H2-type domain-containing protein Neighboring gene Rhomboid-related protein 1 Neighboring gene ANK_REP_REGION domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in vesicle tethering to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    colocalizes_with endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in endoplasmic reticulum-endosome membrane contact site IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in late endosome membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    START domain-containing protein
    NP_001379724.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4900508..4903170
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393331.1NP_001379724.1  START domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q19819
      Conserved Domains (2) summary
      pfam01852
      Location:246441
      START; START domain
      pfam10457
      Location:18192
      MENTAL; Cholesterol-capturing domain