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    ippk-1 Inositol-pentakisphosphate 2-kinase [ Caenorhabditis elegans ]

    Gene ID: 189456, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ippk-1
    Official Full Name
    Inositol-pentakisphosphate 2-kinase
    Primary source
    WormBase:WBGene00012466
    Locus tag
    CELE_Y17G7B.13
    See related
    AllianceGenome:WB:WBGene00012466
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity. Predicted to be involved in inositol phosphate biosynthetic process. Predicted to be active in nucleus. Orthologous to human IPPK (inositol-pentakisphosphate 2-kinase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ippk-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    8
    Sequence:
    Chromosome: II; NC_003280.10 (12042910..12049260)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Triosephosphate isomerase Neighboring gene ncRNA Neighboring gene NAD kinase 2, mitochondrial Neighboring gene Arrestin C-terminal-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in inositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Inositol-pentakisphosphate 2-kinase
    NP_496564.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12042910..12049260
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064163.6 → NP_496564.2  Inositol-pentakisphosphate 2-kinase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496564.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXI1
      Conserved Domains (1) summary
      pfam06090
      Location:21 → 424
      Ins_P5_2-kin; Inositol-pentakisphosphate 2-kinase
    Nucleotide Protein
    Heading Accession and Version

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