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    rpn-6.1 putative 26S proteasome regulatory subunit rpn-6.1 [ Caenorhabditis elegans ]

    Gene ID: 175972, updated on 9-Dec-2024

    Summary

    Official Symbol
    rpn-6.1
    Official Full Name
    putative 26S proteasome regulatory subunit rpn-6.1
    Primary source
    WormBase:WBGene00004462
    Locus tag
    CELE_F57B9.10
    See related
    AllianceGenome:WB:WBGene00004462
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable structural molecule activity. Involved in determination of adult lifespan; proteasome assembly; and ubiquitin-dependent protein catabolic process. Located in nucleus. Is expressed in intestine and pharynx. Orthologous to human PSMD11 (proteasome 26S subunit, non-ATPase 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See rpn-6.1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    7
    Sequence:
    Chromosome: III; NC_003281.10 (6959110..6962001, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Activated in Blocked Unfolded protein response Neighboring gene ncRNA Neighboring gene CCR4-NOT transcription complex subunit let-711 Neighboring gene Putative pyridoxamine 5'-phosphate oxidase Neighboring gene PAN (PolyA-specific riboNucLease) subunit

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural molecule activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of proteasome accessory complex TAS
    Traceable Author Statement
    more info
    PubMed 
    part_of proteasome complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of proteasome regulatory particle, lid subcomplex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative 26S proteasome regulatory subunit rpn-6.1
    NP_001022621.1
    • Confirmed by transcript evidence
    NP_001022622.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      6959110..6962001 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001027450.5NP_001022621.1  putative 26S proteasome regulatory subunit rpn-6.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022621.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20938, Q5DX45
      Conserved Domains (2) summary
      COG5159
      Location:19435
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:311405
      PCI; PCI domain
    2. NM_001027451.6NP_001022622.1  putative 26S proteasome regulatory subunit rpn-6.1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001022622.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20938
      Conserved Domains (2) summary
      COG5159
      Location:1417
      RPN6; 26S proteasome regulatory complex component [Posttranslational modification, protein turnover, chaperones]
      pfam01399
      Location:293387
      PCI; PCI domain