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    col-71 Cuticle collagen 71 [ Caenorhabditis elegans ]

    Gene ID: 173695, updated on 9-Dec-2024

    Summary

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    Official Symbol
    col-71
    Official Full Name
    Cuticle collagen 71
    Primary source
    WormBase:WBGene00000647
    Locus tag
    CELE_Y49F6B.10
    See related
    AllianceGenome:WB:WBGene00000647
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of cuticle. Involved in collagen and cuticulin-based cuticle development. Predicted to be located in membrane and nucleus. Is expressed in hyp7 syncytium and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See col-71 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (3500077..3502570, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene F-box domain-containing protein Neighboring gene RBR-type E3 ubiquitin transferase Neighboring gene ncRNA Neighboring gene Fcf2 pre-rRNA processing C-terminal domain-containing protein Neighboring gene Cyclin-H Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Integration of behavioural tests and transcriptome sequencing of C. elegans reveals how the nematode responds to peanut shell biochar amendment. Li J, et al. Sci Total Environ, 2020 Mar 10. PMID 31972909
    2. Use of an activated beta-catenin to identify Wnt pathway target genes in caenorhabditis elegans, including a subset of collagen genes expressed in late larval development. Jackson BM, et al. G3 (Bethesda), 2014 Apr 16. PMID 24569038, Free PMC Article
    3. Screening for cold tolerance genes in C. elegans, whose expressions are affected by anticancer drugs camptothecin and leptomycin B. Okahata M, et al. Sci Rep, 2024 Mar 5. PMID 38443452, Free PMC Article
    4. A map of the interactome network of the metazoan C. elegans. Li S, et al. Science, 2004 Jan 23. PMID 14704431, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of cuticle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in collagen and cuticulin-based cuticle development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Cuticle collagen 71
    NP_494562.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      3500077..3502570 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062161.5 → NP_494562.1  Cuticle collagen 71 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494562.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9N4U2
      Conserved Domains (2) summary
      pfam01391
      Location:225 → 282
      Collagen; Collagen triple helix repeat (20 copies)
      smart01088
      Location:36 → 88
      Col_cuticle_N; Nematode cuticle collagen N-terminal domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9N4U2.1

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