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    sra-6 Serpentine receptor class alpha-6 [ Caenorhabditis elegans ]

    Gene ID: 191777, updated on 9-Dec-2024

    Summary

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    Official Symbol
    sra-6
    Official Full Name
    Serpentine receptor class alpha-6
    Primary source
    WormBase:WBGene00005032
    Locus tag
    CELE_AH6.10
    See related
    AllianceGenome:WB:WBGene00005032
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception. Located in cilium. Is expressed in head; intestine; nervous system; tail; and in male. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See sra-6 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (9548405..9550818, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class alpha-7 Neighboring gene pseudo Neighboring gene Neuropeptide-Like Protein Neighboring gene Secreted protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The C. elegans homeodomain gene unc-42 regulates chemosensory and glutamate receptor expression. Baran R, et al. Development, 1999 May. PMID 10207148
    2. HLH-14 is a C. elegans achaete-scute protein that promotes neurogenesis through asymmetric cell division. Frank CA, et al. Development, 2003 Dec. PMID 14627726
    3. The Importance of cGMP Signaling in Sensory Cilia for Body Size Regulation in Caenorhabditis elegans. Fujiwara M, et al. Genetics, 2015 Dec. PMID 26434723, Free PMC Article
    4. Mammalian TRPV4 (VR-OAC) directs behavioral responses to osmotic and mechanical stimuli in Caenorhabditis elegans. Liedtke W, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14581619, Free PMC Article
    5. A Memory Circuit for Coping with Impending Adversity. Eliezer Y, et al. Curr Biol, 2019 May 20. PMID 31056393, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sensory perception of chemical stimulus IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cilium IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Serpentine receptor class alpha-6
    NP_496052.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      9548405..9550818 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063651.2 → NP_496052.1  Serpentine receptor class alpha-6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496052.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q09208
      Conserved Domains (1) summary
      pfam02117
      Location:1 → 328
      7TM_GPCR_Sra; Serpentine type 7TM GPCR chemoreceptor Sra
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q09208.1

    Gene LinkOut

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