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    F47F2.1 cAMP-dependent protein kinase catalytic subunit;cAMP-dependent protein kinase, catalytic subunit-like [ Caenorhabditis elegans ]

    Gene ID: 180673, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F47F2.1
    Official Full Name
    cAMP-dependent protein kinase catalytic subunit;cAMP-dependent protein kinase, catalytic subunit-like
    Primary source
    WormBase:WBGene00018569
    Locus tag
    CELE_F47F2.1
    See related
    AllianceGenome:WB:WBGene00018569
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable ATP binding activity and protein kinase activity. Predicted to be involved in cell adhesion and signal transduction. Located in cytoplasm. Orthologous to several human genes including PRKX (protein kinase cAMP-dependent X-linked catalytic subunit). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F47F2.1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (3878571..3893311)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene LIM/homeobox protein lim-4 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene TIL domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    2. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables AMP-activated protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cAMP-dependent protein kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables cAMP-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables cyclic nucleotide-dependent protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of cAMP-dependent protein kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm HDA PubMed 
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cAMP-dependent protein kinase catalytic subunit;cAMP-dependent protein kinase, catalytic subunit-like
    NP_001360750.1
    • Partially confirmed by transcript evidence
    NP_001360751.1
    • Confirmed by transcript evidence
    NP_001360752.1
    • Confirmed by transcript evidence
    NP_001360753.1
    • Confirmed by transcript evidence
    NP_001379961.1
    • Confirmed by transcript evidence
    NP_508671.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      3878571..3893311
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001373267.3 → NP_001360752.1  cAMP-dependent protein kinase catalytic subunit [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IKH2
      Conserved Domains (1) summary
      cd05612
      Location:66 → 357
      STKc_PRKX_like; Catalytic domain of PRKX-like Protein Serine/Threonine Kinases

    2. NM_001392754.1 → NP_001379961.1  cAMP-dependent protein kinase, catalytic subunit-like [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      cl21453
      Location:15 → 306
      PKc_like; Protein Kinases, catalytic domain

    3. NM_001373268.3 → NP_001360753.1  cAMP-dependent protein kinase catalytic subunit [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IKD4
      Conserved Domains (1) summary
      cd05612
      Location:87 → 378
      STKc_PRKX_like; Catalytic domain of PRKX-like Protein Serine/Threonine Kinases

    4. NM_076270.7 → NP_508671.2  cAMP-dependent protein kinase, catalytic subunit-like [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508671.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20541, Q7JP68, Q8MQ39, Q95ZT2
      Conserved Domains (2) summary
      PTZ00263
      Location:80 → 379
      PTZ00263; protein kinase A catalytic subunit; Provisional
      cl21453
      Location:88 → 379
      PKc_like; Protein Kinases, catalytic domain

    5. NM_001373269.3 → NP_001360750.1  cAMP-dependent protein kinase catalytic subunit [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0ILS1
      Conserved Domains (1) summary
      cd05612
      Location:65 → 356
      STKc_PRKX_like; Catalytic domain of PRKX-like Protein Serine/Threonine Kinases

    6. NM_001373270.3 → NP_001360751.1  cAMP-dependent protein kinase catalytic subunit [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IM62
      Conserved Domains (1) summary
      cd05612
      Location:61 → 352
      STKc_PRKX_like; Catalytic domain of PRKX-like Protein Serine/Threonine Kinases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7JP68.1

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