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    gadr-6 Protein zer-1 homolog [ Caenorhabditis elegans ]

    Gene ID: 173273, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gadr-6
    Official Full Name
    Protein zer-1 homolog
    Primary source
    WormBase:WBGene00009823
    Locus tag
    CELE_F47G4.2
    See related
    AllianceGenome:WB:WBGene00009823
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be part of Cul2-RING ubiquitin ligase complex. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gadr-6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (14078193..14082582, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Glycerol-3-phosphate dehydrogenase [NAD(+)] Neighboring gene F-box domain-containing protein Neighboring gene F-box domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Overcoming redundancy: an RNAi enhancer screen for morphogenesis genes in Caenorhabditis elegans. Sawyer JM, et al. Genetics, 2011 Jul. PMID 21527776, Free PMC Article
    2. CCAR-1 works together with the U2AF large subunit UAF-1 to regulate alternative splicing. Lugano DI, et al. RNA Biol, 2024 Jan. PMID 38126797, Free PMC Article
    3. Large-scale RNAi screens identify novel genes that interact with the C. elegans retinoblastoma pathway as well as splicing-related components with synMuv B activity. Ceron J, et al. BMC Dev Biol, 2007 Apr 6. PMID 17417969, Free PMC Article
    4. A genome-wide study of PDZ-domain interactions in C. elegans reveals a high frequency of non-canonical binding. Lenfant N, et al. BMC Genomics, 2010 Nov 26. PMID 21110867, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    part_of Cul2-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Protein zer-1 homolog
    NP_493455.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      14078193..14082582 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061054.9 → NP_493455.1  Protein zer-1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493455.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XTS0
      Conserved Domains (1) summary
      sd00034
      Location:86 → 112
      LRR_AMN1; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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