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    rsp-7 putative splicing factor, arginine/serine-rich 7 [ Caenorhabditis elegans ]

    Gene ID: 174646, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rsp-7
    Official Full Name
    putative splicing factor, arginine/serine-rich 7
    Primary source
    WormBase:WBGene00004704
    Locus tag
    CELE_D2089.1
    See related
    AllianceGenome:WB:WBGene00004704
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in nucleus. Predicted to be active in nucleoplasm. Orthologous to several human genes including SREK1 (splicing regulatory glutamic acid and lysine rich protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rsp-7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    6
    Sequence:
    Chromosome: II; NC_003280.10 (10659206..10662317)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Small nuclear ribonucleoprotein associated homolog 13 Neighboring gene ncRNA Neighboring gene RING-CH-type domain-containing protein Neighboring gene Cysteine-rich DPF motif domain-containing protein 1 Neighboring gene Secreted protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of SR and SR-related genes in Caenorhabditis elegans. Longman D, et al. EMBO J, 2000 Apr 3. PMID 10747030, Free PMC Article
    2. Functional genomic analysis of RNA interference in C. elegans. Kim JK, et al. Science, 2005 May 20. PMID 15790806
    3. A genomewide RNAi screen for genes that affect the stability, distribution and function of P granules in Caenorhabditis elegans. Updike DL, et al. Genetics, 2009 Dec. PMID 19805813, Free PMC Article
    4. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    5. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in mRNA splicing, via spliceosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative splicing factor, arginine/serine-rich 7
    NP_001369854.1
    • Confirmed by transcript evidence
    NP_001379303.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10659206..10662317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393181.1 → NP_001379303.1  putative splicing factor, arginine/serine-rich 7 [Caenorhabditis elegans]

      Status: REVIEWED

      Conserved Domains (1) summary
      cd12259
      Location:11 → 87
      RRM_SRSF11_SREK1; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 11 (SRSF11), splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins

    2. NM_001383939.2 → NP_001369854.1  putative splicing factor, arginine/serine-rich 7 [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O01159, P90797, Q8STE7
      Conserved Domains (2) summary
      cd12259
      Location:11 → 87
      RRM_SRSF11_SREK1; RNA recognition motif (RRM) found in serine/arginine-rich splicing factor 11 (SRSF11), splicing regulatory glutamine/lysine-rich protein 1 (SREK1) and similar proteins
      cl17169
      Location:159 → 245
      RRM_SF; RNA recognition motif (RRM) superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O01159.3

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