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    argF ornithine carbamoyltransferase ArgF [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 944844, updated on 3-Dec-2024

    Summary

    Official Symbol
    argF
    Official Full Name
    ornithine carbamoyltransferase ArgF
    Primary source
    ECOCYC:EG10067
    Locus tag
    b0273
    See related
    ASAP:ABE-0000939
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0274
    Summary
    argI and argF have same enzyme activity. [More information is available at EcoGene: EG10067]. In the test tube, not in the cell, a family of four isoenzymes forms by assortment of two closely similar polypeptides, the chain F-monomer and chain I-monomer, to give active trimers FFF, FFI, FII, and III. [More information is available at EcoCyc: EG10067].
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    Genomic context

    Sequence:
    NC_000913.3 (289301..290305, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene putative xylosidase/arabinosidase Neighboring gene DNA-binding transcriptional repressor XynR Neighboring gene putative translational regulatory protein ArgL Neighboring gene protein YkgS Neighboring gene IS1 family protein InsB Neighboring gene IS1 family protein InsA

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables amino acid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ornithine carbamoyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ornithine carbamoyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables ornithine carbamoyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in L-arginine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in arginine biosynthetic process via ornithine IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in arginine biosynthetic process via ornithine NAS
    Non-traceable Author Statement
    more info
    PubMed 
    involved_in citrulline biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in citrulline biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in ornithine metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ornithine carbamoyltransferase ArgF
    NP_414807.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      289301..290305 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414807.1 ornithine carbamoyltransferase ArgF [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414807.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A6N8NMF6, A0A8T6A4I6
      Conserved Domains (1) summary
      PRK03515
      Location:1332
      PRK03515; ornithine carbamoyltransferase subunit I; Provisional