U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ykfI toxin of the YkfI-YafW toxin-antitoxin system [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946726, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ykfI
    Official Full Name
    toxin of the YkfI-YafW toxin-antitoxin system
    Primary source
    ECOCYC:G6120
    Locus tag
    b0245
    See related
    ASAP:ABE-0000836
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK0246
    Summary
    ykfI, ypjF and yeeV are paralogs. [More information is available at EcoGene: EG14333]. Episomal expression of ykfI causes inhibition of cell growth and decreased viability, compared to wild type , and this phenotype is suppressed by coexpression of yafW . [More information is available at EcoCyc: G6120].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (263328..263669, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene tRNA-Thr Neighboring gene pseudo Neighboring gene antitoxin of the YkfI-YafW toxin-antitoxin pair Neighboring gene DUF987 domain-containing protein YkfH

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Temporal gene-expression in Escherichia coli K-12 biofilms. Domka J, et al. Environ Microbiol, 2007 Feb. PMID 17222132
    2. Prophages and bacterial genomics: what have we learned so far? Casjens S. Mol Microbiol, 2003 Jul. PMID 12886937
    3. A novel family of Escherichia coli toxin-antitoxin gene pairs. Brown JM, et al. J Bacteriol, 2003 Nov. PMID 14594833, Free PMC Article
    4. A functional update of the Escherichia coli K-12 genome. Serres MH, et al. Genome Biol, 2001. PMID 11574054, Free PMC Article
    5. The binary protein-protein interaction landscape of Escherichia coli. Rajagopala SV, et al. Nat Biotechnol, 2014 Mar. PMID 24561554, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Process Evidence Code Pubs
    acts_upstream_of_or_within negative regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    toxin of the YkfI-YafW toxin-antitoxin system

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      263328..263669 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_414779.1 toxin of the YkfI-YafW toxin-antitoxin system [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_414779.1

      Status: PROVISIONAL

      UniProtKB/Swiss-Prot
      P77692
      Conserved Domains (1) summary
      pfam06755
      Location:1 → 108
      CbtA_toxin; CbtA_toxin of type IV toxin-antitoxin system
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.