U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    argH argininosuccinate lyase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 948463, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    argH
    Official Full Name
    argininosuccinate lyase
    Primary source
    ECOCYC:EG11223
    Locus tag
    b3960
    See related
    ASAP:ABE-0012969
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3951
    Summary
    Argininosuccinate lyase catalyzes the final step in the L-arginine biosynthesis pathway. [More information is available at EcoCyc: EG11223].
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (4156850..4158223)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene N-acetylglutamylphosphate reductase Neighboring gene acetylglutamate kinase Neighboring gene ncRNA Neighboring gene DNA-binding transcriptional dual regulator OxyR Neighboring gene soluble pyridine nucleotide transhydrogenase

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Dual regulation by arginine of the expression of the Escherichia coli argECBH operon. Kryzek RA, et al. J Bacteriol, 1976 Apr. PMID 770426, Free PMC Article
    2. Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli. Bhaumik P, et al. Acta Crystallogr D Biol Crystallogr, 2004 Nov. PMID 15502303
    3. The determination by radiochemical assay of argininosuccinase produced in an Escherichia coli system in vitro. Zidwick MJ, et al. Biochem J, 1982 Dec 1. PMID 6762207, Free PMC Article
    4. Stationary phase expression of the arginine biosynthetic operon argCBH in Escherichia coli. Weerasinghe JP, et al. BMC Microbiol, 2006 Feb 22. PMID 16504055, Free PMC Article
    5. Nucleotide sequence of Escherichia coli argB and argC genes: comparison of N-acetylglutamate kinase and N-acetylglutamate-gamma-semialdehyde dehydrogenase with homologous and analogous enzymes. Parsot C, et al. Gene, 1988 Sep 7. PMID 2851495

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. crystal structure of argininosuccinate lyase
      Title: Structure determination and refinement at 2.44 A resolution of argininosuccinate lyase from Escherichia coli.
    Submit: New GeneRIF Correction

    Pathways from PubChem

    Go to the top of the page

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables argininosuccinate lyase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables argininosuccinate lyase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables argininosuccinate lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-arginine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in arginine biosynthetic process via ornithine IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in arginine biosynthetic process via ornithine IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    argininosuccinate lyase
    NP_418395.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      4156850..4158223
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_418395.1 argininosuccinate lyase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_418395.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2X3KKI2
      Conserved Domains (1) summary
      PRK04833
      Location:1 → 455
      PRK04833; argininosuccinate lyase; Provisional
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.