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    MFG1 Mfg1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851365, updated on 27-Dec-2024

    Summary

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    Official Symbol
    MFG1
    Official Full Name
    Mfg1p
    Primary source
    SGD:S000002392
    Locus tag
    YDL233W
    See related
    AllianceGenome:SGD:S000002392; FungiDB:YDL233W; VEuPathDB:YDL233W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See MFG1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (36797..38173)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene Ypd1p Neighboring gene GTPase-activating protein GYP7 Neighboring gene olichyl-diphosphooligosaccharide--protein glycotransferase OST4 Neighboring gene Bre4p

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_001136.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identifying molecular features that are associated with biological function of intrinsically disordered protein regions. Zarin T, et al. Elife, 2021 Feb 22. PMID 33616531, Free PMC Article
    2. Composition-based prediction and rational manipulation of prion-like domain recruitment to stress granules. Boncella AE, et al. Proc Natl Acad Sci U S A, 2020 Mar 17. PMID 32127480, Free PMC Article
    3. The Absence of the Transcription Factor Yrr1p, Identified from Comparative Genome Profiling, Increased Vanillin Tolerance Due to Enhancements of ABC Transporters Expressing, rRNA Processing and Ribosome Biogenesis in Saccharomyces cerevisiae. Wang X, et al. Front Microbiol, 2017. PMID 28360888, Free PMC Article
    4. Global gene deletion analysis exploring yeast filamentous growth. Ryan O, et al. Science, 2012 Sep 14. PMID 22984072
    5. Transcription factor regulation and chromosome dynamics during pseudohyphal growth. Mayhew D, et al. Mol Biol Cell, 2014 Sep 1. PMID 25009286, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in nucleus HDA PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of transcription regulator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Mfg1p
    NP_010048.1
    • Regulator of filamentous growth; interacts with FLO11 promoter and regulates FLO11 expression; binds to transcription factors Flo8p and Mss11p; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YDL233W is not an essential gene

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      36797..38173
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180293.1 → NP_010048.1  TPA: Mfg1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010048.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VRC3, Q07684
      UniProtKB/TrEMBL
      A6ZXA1, B3LHA9, C7GJQ2, N1P5M5
      Conserved Domains (2) summary
      pfam01803
      Location:151 → 393
      LIM_bind; LIM-domain binding protein
      pfam03154
      Location:24 → 137
      Atrophin-1; Atrophin-1 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q07684.1

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