U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    BET1 Bet1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854813, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    BET1
    Official Full Name
    Bet1p
    Primary source
    SGD:S000001266
    Locus tag
    YIL004C
    See related
    AllianceGenome:SGD:S000001266; FungiDB:YIL004C; VEuPathDB:YIL004C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    SLY12
    Summary
    Enables SNAP receptor activity. Involved in endoplasmic reticulum to Golgi vesicle-mediated transport; retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; and vesicle fusion. Located in COPII-coated ER to Golgi transport vesicle and endoplasmic reticulum membrane. Part of SNARE complex. Human ortholog(s) of this gene implicated in uterine fibroid. Orthologous to several human genes including BET1 (Bet1 golgi vesicular membrane trafficking protein). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See BET1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    2
    Sequence:
    Chromosome: IX; NC_001141.2 (347946..348505, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene NAD+ transporter Neighboring gene protein disulfide isomerase EPS1 Neighboring gene iron-sulfur cluster assembly protein CFD1 Neighboring gene Cmi7p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Bos1p, a membrane protein required for ER to Golgi transport in yeast, co-purifies with the carrier vesicles and with Bet1p and the ER membrane. Newman AP, et al. EMBO J, 1992 Oct. PMID 1396561, Free PMC Article
    2. Bet1p activates the v-SNARE Bos1p. Stone S, et al. Mol Biol Cell, 1997 Jul. PMID 9243499, Free PMC Article
    3. Nucleotide sequence and analysis of the centromeric region of yeast chromosome IX. Voss H, et al. Yeast, 1995 Jan. PMID 7762303
    4. Characterization of new mutants in the early part of the yeast secretory pathway isolated by a [3H]mannose suicide selection. Newman AP, et al. J Cell Biol, 1987 Oct. PMID 3312234, Free PMC Article
    5. The BOS1 gene encodes an essential 27-kD putative membrane protein that is required for vesicular transport from the ER to the Golgi complex in yeast. Shim J, et al. J Cell Biol, 1991 Apr. PMID 2007627, Free PMC Article

    See all (84) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables SNAP receptor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables SNAP receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in membrane fusion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in vesicle fusion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in COPII-coated ER to Golgi transport vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of SNARE complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endomembrane system IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Bet1p
    NP_012262.3
    • Type II membrane protein required for vesicular transport; required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      347946..348505 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179354.3 → NP_012262.3  TPA: Bet1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012262.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVS6, P22804
      UniProtKB/TrEMBL
      A6ZVR4, B3LTL3, C8ZAP5, G2WGE2, N1P0P7
      Conserved Domains (1) summary
      cd15853
      Location:55 → 112
      SNARE_Bet1; SNARE motif of Bet1
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P22804.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.