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    alkB2 alkane-1 monooxygenase [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 879517, updated on 11-Sep-2024

    Summary

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    Gene symbol
    alkB2
    Gene description
    alkane-1 monooxygenase
    Locus tag
    PA1525
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (1659413..1660546, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene hypothetical protein Neighboring gene xanthine dehydrogenase Neighboring gene xanthine dehydrogenase Neighboring gene transcriptional regulator Neighboring gene hypothetical protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional characterization of genes involved in alkane oxidation by Pseudomonas aeruginosa. Smits TH, et al. Antonie Van Leeuwenhoek, 2003. PMID 14574114
    2. Functional analysis of alkane hydroxylases from gram-negative and gram-positive bacteria. Smits TH, et al. J Bacteriol, 2002 Mar. PMID 11872725, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by PseudoCAP

    Function Evidence Code Pubs
    enables alkane 1-monooxygenase activity IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within alkane catabolic process IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    alkane-1 monooxygenase
    NP_250216.1
    • Product name confidence: class 1 (Function experimentally demonstrated in P. aeruginosa)

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      1659413..1660546 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_250216.1 alkane-1 monooxygenase [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_250216.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A097BPW7, A0A3M5DR12, B3GCK4, Q6H927
      Conserved Domains (1) summary
      cd03512
      Location:43 → 360
      Alkane-hydroxylase; Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6H941.1

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