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    PA2824 sensor/response regulator hybrid protein [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 878885, updated on 10-Oct-2024

    Summary

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    Gene symbol
    PA2824
    Gene description
    sensor/response regulator hybrid protein
    Locus tag
    PA2824
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3177090..3179450)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene glutathione S-transferase Neighboring gene hypothetical protein Neighboring gene hypothetical protein Neighboring gene transcriptional regulator Neighboring gene glutathione peroxidase Neighboring gene methionine sulfoxide reductase B

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Controlling chronic Pseudomonas aeruginosa infections by strategically interfering with the sensory function of SagS. Dingemans J, et al. Mol Microbiol, 2019 May. PMID 30710463, Free PMC Article
    2. The Pseudomonas aeruginosa PA01 gene collection. Labaer J, et al. Genome Res, 2004 Oct. PMID 15489342, Free PMC Article
    3. SagS contributes to the motile-sessile switch and acts in concert with BfiSR to enable Pseudomonas aeruginosa biofilm formation. Petrova OE, et al. J Bacteriol, 2011 Dec. PMID 21949078, Free PMC Article
    4. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    5. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Our findings suggest that interference with the biofilm or tolerance regulatory circuits of SagS affects P. aeruginosa pathogenicity in chronic but not acute infections.
      Title: Controlling chronic Pseudomonas aeruginosa infections by strategically interfering with the sensory function of SagS.
    2. SagS interacts directly with BfiS and indirectly with BfiR to enable biofilm formation.
      Title: SagS contributes to the motile-sessile switch and acts in concert with BfiSR to enable Pseudomonas aeruginosa biofilm formation.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    General protein information

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    Preferred Names
    sensor/response regulator hybrid protein
    NP_251514.1
    • 'Product name confidence: class 3 (Function proposed based on presence of conserved amino acid motif, structural feature or limited sequence similarity to an experimentally studied gene)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3177090..3179450
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251514.1 sensor/response regulator hybrid protein [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251514.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A2R3IT00
      Conserved Domains (2) summary
      PRK11829
      Location:29 → 241
      PRK11829; biofilm formation regulator HmsP; Provisional
      PRK11107
      Location:260 → 783
      PRK11107; hybrid sensory histidine kinase BarA; Provisional
    Nucleotide Protein
    Heading Accession and Version

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