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    PA2852 hypothetical protein [ Pseudomonas aeruginosa PAO1 ]

    Gene ID: 882634, updated on 24-Aug-2024

    Summary

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    Gene symbol
    PA2852
    Gene description
    hypothetical protein
    Locus tag
    PA2852
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Pseudomonas aeruginosa PAO1 (strain: PAO1)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales; Pseudomonadaceae; Pseudomonas
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    Genomic context

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    Sequence:
    NC_002516.2 (3205123..3206253, complement)

    NC_002516.2Genomic Context describing neighboring genes Neighboring gene organic hydroperoxide resistance protein Neighboring gene elongation factor P Neighboring gene tRNA-Ser Neighboring gene outer membrane lipoprotein OprI

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_002516.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Complex Structure of Pseudomonas aeruginosa Arginine Rhamnosyltransferase EarP with Its Acceptor Elongation Factor P. He C, et al. J Bacteriol, 2019 Jul 1. PMID 31010899, Free PMC Article
    2. Arginine-rhamnosylation as new strategy to activate translation elongation factor P. Lassak J, et al. Nat Chem Biol, 2015 Apr. PMID 25686373, Free PMC Article
    3. Pseudomonas Genome Database: facilitating user-friendly, comprehensive comparisons of microbial genomes. Winsor GL, et al. Nucleic Acids Res, 2009 Jan. PMID 18978025, Free PMC Article
    4. Defining the Pseudomonas aeruginosa SOS response and its role in the global response to the antibiotic ciprofloxacin. Cirz RT, et al. J Bacteriol, 2006 Oct. PMID 17015649, Free PMC Article
    5. Cystic fibrosis sputum supports growth and cues key aspects of Pseudomonas aeruginosa physiology. Palmer KL, et al. J Bacteriol, 2005 Aug. PMID 16030221, Free PMC Article

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. detailed structural and biochemical characterization of the EF-P-specific rhamnosyltransferase EarP from P. aeruginosa demonstrates that sugar donor TDP-Rha binding enhances acceptor EF-P binding to EarP
      Title: Complex Structure of Pseudomonas aeruginosa Arginine Rhamnosyltransferase EarP with Its Acceptor Elongation Factor P.
    2. DUF2331 containing proteins, now designated as EarP, represent a class of bacterial glycosyltransferases. Specifically, EarP activates the polyproline-specific bacterial translation elongation factor P (EF-P) by rhamnosylation of a conserved arginine (R32) using dTDP-rhamnose as a substrate. The name EarP stands for: EF-P Arginine Rhamnosyl-transferase essential for post-translational activation.
      Title: Arginine-rhamnosylation as new strategy to activate translation elongation factor P.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    General protein information

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    Preferred Names
    hypothetical protein
    NP_251542.1
    • 'Product name confidence: class 4 (Homologs of previously reported genes of unknown function, or no similarity to any previously reported sequences)'

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_002516.2 Reference assembly

      Range
      3205123..3206253 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_251542.1 hypothetical protein PA2852 [Pseudomonas aeruginosa PAO1]

      See identical proteins and their annotated locations for NP_251542.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      Q9HZZ1
      Conserved Domains (1) summary
      COG4394
      Location:1 → 376
      EarP; Elongation-Factor P (EF-P) rhamnosyltransferase EarP [Translation, ribosomal structure and biogenesis]
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9HZZ1.1

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