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    Gm3604 predicted gene 3604 [ Mus musculus (house mouse) ]

    Gene ID: 100041979, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Gm3604provided by MGI
    Official Full Name
    predicted gene 3604provided by MGI
    Primary source
    MGI:MGI:3781781
    See related
    Ensembl:ENSMUSG00000094942 AllianceGenome:MGI:3781781
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA binding activity; DNA-binding transcription repressor activity, RNA polymerase II-specific; and protein-macromolecule adaptor activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Orthologous to several human genes including ZNF234 (zinc finger protein 234); ZNF254 (zinc finger protein 254); and ZNF28 (zinc finger protein 28). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    See Gm3604 in Genome Data Viewer
    Location:
    13 B3; 13 32.74 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (62514534..62561441, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (62367716..62411972, complement)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_34770 Neighboring gene predicted gene, 19792 Neighboring gene predicted gene, 53216 Neighboring gene STARR-positive B cell enhancer mm9_chr13:62484434-62484734 Neighboring gene selenoprotein K, pseudogene 6 Neighboring gene STARR-seq mESC enhancer starr_34771 Neighboring gene predicted gene, 23855 Neighboring gene predicted gene, 53788 Neighboring gene zinc finger protein 935 Neighboring gene STARR-positive B cell enhancer ABC_E7245

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables damaged DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein LOC100041979

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001162910.1 → NP_001156382.1  uncharacterized protein LOC100041979

      Status: VALIDATED

      Source sequence(s)
      CT573034
      Consensus CDS
      CCDS79201.1
      UniProtKB/TrEMBL
      A0A087WPN2
      Related
      ENSMUSP00000139845.2, ENSMUST00000187656.7
      Conserved Domains (5) summary
      smart00349
      Location:4 → 45
      KRAB; krueppel associated box
      COG5048
      Location:130 → 558
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:303 → 323
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:4 → 40
      KRAB; KRAB box
      pfam13465
      Location:175 → 200
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      62514534..62561441 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157792.1 → XP_036013685.1  uncharacterized protein LOC100041979 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:98 → 526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:271 → 291
      ZF_C2H2; C2H2 Zn finger [structural motif]

    2. XM_011244440.4 → XP_011242742.1  uncharacterized protein LOC100041979 isoform X2

      See identical proteins and their annotated locations for XP_011242742.1

      Related
      ENSMUSP00000103623.4, ENSMUST00000107989.7
      Conserved Domains (2) summary
      COG5048
      Location:98 → 526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:271 → 291
      ZF_C2H2; C2H2 Zn finger [structural motif]

    3. XM_036157793.1 → XP_036013686.1  uncharacterized protein LOC100041979 isoform X2

      Conserved Domains (2) summary
      COG5048
      Location:98 → 526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:271 → 291
      ZF_C2H2; C2H2 Zn finger [structural motif]

    4. XM_036157794.1 → XP_036013687.1  uncharacterized protein LOC100041979 isoform X3

      Conserved Domains (2) summary
      COG5048
      Location:16 → 415
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:160 → 180
      ZF_C2H2; C2H2 Zn finger [structural motif]

    5. XM_011244438.4 → XP_011242740.1  uncharacterized protein LOC100041979 isoform X1

      Conserved Domains (3) summary
      COG5048
      Location:116 → 544
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:289 → 309
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam01352
      Location:2 → 30
      KRAB; KRAB box

    6. XM_011244441.4 → XP_011242743.1  uncharacterized protein LOC100041979 isoform X2

      See identical proteins and their annotated locations for XP_011242743.1

      Conserved Domains (2) summary
      COG5048
      Location:98 → 526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:271 → 291
      ZF_C2H2; C2H2 Zn finger [structural motif]

    7. XM_036157795.1 → XP_036013688.1  uncharacterized protein LOC100041979 isoform X4

      UniProtKB/TrEMBL
      A0A0J9YU77, A0A1Y7VJ92
      Related
      ENSMUSP00000144048.2, ENSMUST00000202194.2
      Conserved Domains (1) summary
      pfam01352
      Location:4 → 44
      KRAB; KRAB box
    Nucleotide Protein Strain
    Heading Accession and Version

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