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    Ccdc59 coiled-coil domain containing 59 [ Mus musculus (house mouse) ]

    Gene ID: 52713, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ccdc59provided by MGI
    Official Full Name
    coiled-coil domain containing 59provided by MGI
    Primary source
    MGI:MGI:1289302
    See related
    Ensembl:ENSMUSG00000019897 AllianceGenome:MGI:1289302
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D10Ertd718e; 2300004H16Rik
    Summary
    Predicted to be located in nucleus. Is expressed in early conceptus; embryo; extraembryonic component; oocyte; and primitive endoderm. Orthologous to human CCDC59 (coiled-coil domain containing 59). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in CNS E11.5 (RPKM 15.4), placenta adult (RPKM 12.8) and 23 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ccdc59 in Genome Data Viewer
    Location:
    10 D1; 10 55.12 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (105677340..105683371)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (105841479..105847510)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer mm9_chr10:105012433-105012734 Neighboring gene predicted gene 15663 Neighboring gene STARR-seq mESC enhancer starr_27763 Neighboring gene STARR-seq mESC enhancer starr_27765 Neighboring gene methyltransferase like 25 Neighboring gene STARR-positive B cell enhancer ABC_E9803 Neighboring gene STARR-positive B cell enhancer ABC_E6919 Neighboring gene STARR-seq mESC enhancer starr_27766 Neighboring gene STARR-seq mESC enhancer starr_27767 Neighboring gene predicted gene, 25342 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Gineste C, et al. Neuromuscul Disord, 2013 Apr. PMID 23375831
    2. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    5. Genetic determinants of micronucleus formation in vivo. Adams DJ, et al. Nature, 2024 Mar. PMID 38355793, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    thyroid transcription factor 1-associated protein 26
    Names
    TTF-1-associated protein 26
    coiled-coil domain-containing protein 59

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025602.3 → NP_079878.1  thyroid transcription factor 1-associated protein 26

      See identical proteins and their annotated locations for NP_079878.1

      Status: PROVISIONAL

      Source sequence(s)
      AC132471
      Consensus CDS
      CCDS24158.1
      UniProtKB/Swiss-Prot
      Q8BZ86, Q8R2N0, Q9CR69, Q9CV91
      Related
      ENSMUSP00000020049.9, ENSMUST00000020049.9
      Conserved Domains (2) summary
      pfam08524
      Location:138 → 239
      rRNA_processing; rRNA processing
      cl00489
      Location:164 → 211
      60KD_IMP; 60Kd inner membrane protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      105677340..105683371
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8R2N0.2 GenPept UniProtKB/Swiss-Prot:Q8R2N0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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