U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    aroB 3-dehydroquinate synthase [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947927, updated on 3-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    aroB
    Official Full Name
    3-dehydroquinate synthase
    Primary source
    ECOCYC:EG10074
    Locus tag
    b3389
    See related
    ASAP:ABE-0011067
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK3376
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Sequence:
    NC_000913.3 (3517398..3518486, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene DNA adenine methyltransferase Neighboring gene cell division protein DamX Neighboring gene shikimate kinase 1 Neighboring gene DNA utilization protein HofQ Neighboring gene DNA utilization protein HofP

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Isotope effects in 3-dehydroquinate synthase and dehydratase. Mechanistic implications. Rotenberg SL, et al. J Biol Chem, 1978 Apr 10. PMID 344312
    2. 5-Dehydro-3-deoxy-D-arabino-heptulosonic acid 7-phosphate. An intermediate in the 3-dehydroquinate synthase reaction. Maitra US, et al. J Biol Chem, 1978 Aug 10. PMID 353051
    3. The shikimate pathway. IV. 3-dehydroquinate synthetase of E. coli. Substrate analogs and inhibitors. Le Marechal P, et al. Biochimie, 1976 Nov 13. PMID 793638
    4. Dehydroquinate synthase: the role of divalent metal cations and of nicotinamide adenine dinucleotide in catalysis. Bender SL, et al. Biochemistry, 1989 Sep 19. PMID 2514789
    5. The complete amino acid sequence of 3-dehydroquinate synthase of Escherichia coli K12. Millar G, et al. FEBS Lett, 1986 May 5. PMID 3009224

    See all (25) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

    Go to the top of the page

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables 3-dehydroquinate synthase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables 3-dehydroquinate synthase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables 3-dehydroquinate synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables 3-dehydroquinate synthase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables NAD+ binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables lyase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables zinc ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in amino acid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in aromatic amino acid family biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in aromatic amino acid family biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within aromatic amino acid family biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    involved_in chorismate biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    3-dehydroquinate synthase
    NP_417848.1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3517398..3518486 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417848.1 3-dehydroquinate synthase [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417848.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A5B9AN42
      Conserved Domains (1) summary
      PRK00002
      Location:4 → 360
      aroB; 3-dehydroquinate synthase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.