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    flhA flagellar biosynthesis protein FlhA [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 946390, updated on 3-Dec-2024

    Summary

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    Official Symbol
    flhA
    Official Full Name
    flagellar biosynthesis protein FlhA
    Primary source
    ECOCYC:G370
    Locus tag
    b1879
    See related
    ASAP:ABE-0006272
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK1880; flaH
    Summary
    Flagellar regulon. [More information is available at EcoGene: EG14273]. FlhA is one of six integral membrane components of the flagellar export apparatus. [More information is available at EcoCyc: G370].
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    Genomic context

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    Sequence:
    NC_000913.3 (1962972..1965050, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene protein YecT Neighboring gene flagellar protein FlhE Neighboring gene flagellar biosynthesis protein FlhB Neighboring gene chemotaxis protein CheZ Neighboring gene chemotaxis protein CheY

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Crystallization and preliminary X-ray analysis of the C-terminal cytoplasmic domain of FlhA, a membrane-protein subunit of the bacterial flagellar type III protein-export apparatus. Saijo-Hamano Y, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun, 2005 Jun 1. PMID 16511106, Free PMC Article
    2. FliK-Driven Conformational Rearrangements of FlhA and FlhB Are Required for Export Switching of the Flagellar Protein Export Apparatus. Minamino T, et al. J Bacteriol, 2020 Jan 15. PMID 31712281, Free PMC Article
    3. Assembly and stability of flagellar motor in Escherichia coli. Li H, et al. Mol Microbiol, 2011 May. PMID 21244534
    4. Incomplete flagellar structures in Escherichia coli mutants. Suzuki T, et al. J Bacteriol, 1981 Feb. PMID 7007337, Free PMC Article
    5. Flagella-Driven Motility of Bacteria. Nakamura S, et al. Biomolecules, 2019 Jul 14. PMID 31337100, Free PMC Article

    See all (48) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. FliK-Driven Conformational Rearrangements of FlhA and FlhB Are Required for Export Switching of the Flagellar Protein Export Apparatus.
      Title: FliK-Driven Conformational Rearrangements of FlhA and FlhB Are Required for Export Switching of the Flagellar Protein Export Apparatus.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in bacterial-type flagellum assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in bacterial-type flagellum assembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within bacterial-type flagellum assembly IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in bacterial-type flagellum organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in bacterial-type flagellum-dependent cell motility NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in chemotaxis NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in protein secretion IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein secretion by the type III secretion system NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in bacterial-type flagellum NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in bacterial-type flagellum secretion apparatus NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of type III protein secretion system complex NAS
    Non-traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    flagellar biosynthesis protein FlhA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      1962972..1965050 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_416393.1 flagellar biosynthesis protein FlhA [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_416393.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8H9XP28, A0A8S7TBJ8
      Conserved Domains (1) summary
      PRK06012
      Location:2 → 691
      flhA; flagellar type III secretion system protein FlhA
    Nucleotide Protein
    Heading Accession and Version

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