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    glcD glycolate dehydrogenase, putative FAD-linked subunit [ Escherichia coli str. K-12 substr. MG1655 ]

    Gene ID: 947353, updated on 3-Dec-2024

    Summary

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    Official Symbol
    glcD
    Official Full Name
    glycolate dehydrogenase, putative FAD-linked subunit
    Primary source
    ECOCYC:G7545
    Locus tag
    b2979
    See related
    ASAP:ABE-0009773
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
    Lineage
    Bacteria; Pseudomonadota; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
    Also known as
    ECK2974; gox; yghM
    Summary
    Glycolate oxidase catalyzes the first step in the utilization of glycolate as the sole source of carbon . [More information is available at EcoCyc: G7545].
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    Genomic context

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    Sequence:
    NC_000913.3 (3126522..3128021, complement)

    NC_000913.3Genomic Context describing neighboring genes Neighboring gene glycolate dehydrogenase, putative iron-sulfur subunit Neighboring gene glycolate dehydrogenase, putative FAD-binding subunit Neighboring gene DNA-binding transcriptional dual regulator GlcC Neighboring gene putative DNA-binding transcriptional regulator YghO Neighboring gene IS5 family transposase and trans-activator

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_000913.3

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Glycolate oxidoreductase in Escherichia coli. Lord JM. Biochim Biophys Acta, 1972 May 25. PMID 4557653
    2. The intracellular localization of glycolate oxidoreductase in Escherichia coli. Sallal AK, et al. FEBS Lett, 1989 Dec 4. PMID 2689218
    3. The gene yghK linked to the glc operon of Escherichia coli encodes a permease for glycolate that is structurally and functionally similar to L-lactate permease. Núñez MF, et al. Microbiology (Reading), 2001 Apr. PMID 11283302
    4. Cross-induction of glc and ace operons of Escherichia coli attributable to pathway intersection. Characterization of the glc promoter. Pellicer MT, et al. J Biol Chem, 1999 Jan 15. PMID 9880556
    5. Over 1000 genes are involved in the DNA damage response of Escherichia coli. Khil PP, et al. Mol Microbiol, 2002 Apr. PMID 11967071

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by EcoCyc

    Function Evidence Code Pubs
    enables (S)-2-hydroxy-acid oxidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables D-2-hydroxy-acid dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables FAD binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycolate dehydrogenase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables glycolate dehydrogenase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within glycolate catabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of glycolate oxidase complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    glycolate dehydrogenase, putative FAD-linked subunit
    NP_417453.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_000913.3 Reference assembly

      Range
      3126522..3128021 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NP_417453.1 glycolate dehydrogenase, putative FAD-linked subunit [Escherichia coli str. K-12 substr. MG1655]

      See identical proteins and their annotated locations for NP_417453.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A8T5Z9D2
      Conserved Domains (1) summary
      PRK11230
      Location:1 → 499
      PRK11230; glycolate oxidase subunit GlcD; Provisional
    Nucleotide Protein
    Heading Accession and Version

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