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    Lnpk Lunapark [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 35842, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Lnpkprovided by FlyBase
    Official Full Name
    Lunaparkprovided by FlyBase
    Primary source
    FLYBASE:FBgn0033309
    Locus tag
    Dmel_CG8735
    See related
    AllianceGenome:FB:FBgn0033309
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG8735; Dmel\CG8735; DmLnp
    Summary
    Predicted to be involved in endoplasmic reticulum tubular network organization. Located in endomembrane system. Is expressed in adult head. Orthologous to human LNPK (lunapark, ER junction formation factor). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See Lnpk in Genome Data Viewer
    Location:
    44D4-44D4; 2-59 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (8596972..8599962, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (4484477..4487467, complement)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene regular Neighboring gene uncharacterized protein Neighboring gene Calcium-independent receptor for alpha-latrotoxin

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Lunapark stabilizes nascent three-way junctions in the endoplasmic reticulum. Chen S, et al. Proc Natl Acad Sci U S A, 2015 Jan 13. PMID 25548161, Free PMC Article
    2. A constant light-genetic screen identifies KISMET as a regulator of circadian photoresponses. Dubruille R, et al. PLoS Genet, 2009 Dec. PMID 20041201, Free PMC Article
    3. Protein correlation profiles identify lipid droplet proteins with high confidence. Krahmer N, et al. Mol Cell Proteomics, 2013 May. PMID 23319140, Free PMC Article
    4. The RNA-Binding ATPase, Armitage, Couples piRNA Amplification in Nuage to Phased piRNA Production on Mitochondria. Ge DT, et al. Mol Cell, 2019 Jun 6. PMID 31076285, Free PMC Article
    5. Quantitative proteomics and phosphoproteomics reveal insights into mechanisms of ocnus function in Drosophila testis development. Zheng Y, et al. BMC Genomics, 2023 May 26. PMID 37237333, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum tubular network organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum tubular network organization IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endomembrane system HDA PubMed 
    is_active_in endoplasmic reticulum tubular network IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    lunapark
    Names
    CG8735-PA
    CG8735-PB
    Lnpk-PA
    Lnpk-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      8596972..8599962 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001299272.1 → NP_001286201.1  lunapark, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001286201.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K2N0
      Conserved Domains (1) summary
      pfam10058
      Location:247 → 297
      zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein

    2. NM_136551.3 → NP_610395.1  lunapark, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_610395.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7K2N0
      Related
      FBpp0087809
      Conserved Domains (1) summary
      pfam10058
      Location:247 → 297
      zinc_ribbon_10; Predicted integral membrane zinc-ribbon metal-binding protein
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7K2N0 Q7K2N0

    Gene LinkOut

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