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    CG30275 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246522, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG30275provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050275
    Locus tag
    Dmel_CG30275
    See related
    AllianceGenome:FB:FBgn0050275
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG13520; Dmel\CG30275
    Summary
    Predicted to enable oxidoreductase activity. Is expressed in spermatogonium. Human ortholog(s) of this gene implicated in spermatogenic failure 84. Orthologous to human CFAP61 (cilia and flagella associated protein 61). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG30275 in Genome Data Viewer
    Location:
    59A3-59A3; 2-101 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22707794..22712724)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18595299..18600229)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene antisense RNA:CR43735 Neighboring gene Odorant-binding protein 58c Neighboring gene Odorant-binding protein 58d Neighboring gene uncharacterized protein Neighboring gene jitterbug Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome-wide phenotypic RNAi screen in the Drosophila wing: global parameters. López-Varea A, et al. G3 (Bethesda), 2021 Dec 8. PMID 34599819, Free PMC Article
    2. Survey of the Ciliary Motility Machinery of Drosophila Sperm and Ciliated Mechanosensory Neurons Reveals Unexpected Cell-Type Specific Variations: A Model for Motile Ciliopathies. Zur Lage P, et al. Front Genet, 2019. PMID 30774648, Free PMC Article
    3. In vivo analysis of proteomes and interactomes using Parallel Affinity Capture (iPAC) coupled to mass spectrometry. Rees JS, et al. Mol Cell Proteomics, 2011 Jun. PMID 21447707, Free PMC Article
    4. Genes conserved in bilaterians but jointly lost with Myc during nematode evolution are enriched in cell proliferation and cell migration functions. Erives AJ. Dev Genes Evol, 2015 Sep. PMID 26173873, Free PMC Article
    5. The genetic basis for variation in olfactory behavior in Drosophila melanogaster. Arya GH, et al. Chem Senses, 2015 May. PMID 25687947, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in sperm flagellum assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in sperm flagellum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG30275-PL
    CG30275-PM
    CG30275-PN
    NP_001137738.2
    NP_726231.4
    NP_788430.3

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22707794..22712724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_176250.4 → NP_788430.3  uncharacterized protein Dmel_CG30275, isoform M [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_788430.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q7KVK5
      Conserved Domains (1) summary
      pfam16092
      Location:5 → 279
      DUF4821; Domain of unknown function (DUF4821)

    2. NM_166544.4 → NP_726231.4  uncharacterized protein Dmel_CG30275, isoform L [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_726231.4

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8MME7
      Conserved Domains (1) summary
      pfam16092
      Location:5 → 266
      DUF4821; Domain of unknown function (DUF4821)

    3. NM_001144266.2 → NP_001137738.2  uncharacterized protein Dmel_CG30275, isoform N [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001137738.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      B7YZN9
      Conserved Domains (1) summary
      pfam16092
      Location:5 → 266
      DUF4821; Domain of unknown function (DUF4821)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B7YZN9 B7YZN9
    Q7KVK5 Q7KVK5
    Q8MME7 Q8MME7
    Q8MZE1 Q8MZE1

    Gene LinkOut

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