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    NtR NtR [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 43935, updated on 9-Dec-2024

    Summary

    Official Symbol
    NtRprovided by FlyBase
    Official Full Name
    NtRprovided by FlyBase
    Primary source
    FLYBASE:FBgn0029147
    Locus tag
    Dmel_CG6698
    See related
    AllianceGenome:FB:FBgn0029147
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    anon-WO0138359.3; CG6698; Dmel\CG6698; DNtR; NTR
    Summary
    Predicted to enable excitatory extracellular ligand-gated monoatomic ion channel activity and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Predicted to be involved in chemical synaptic transmission; monoatomic ion transmembrane transport; and regulation of membrane potential. Predicted to be located in membrane. Predicted to be part of acetylcholine-gated channel complex. Predicted to be active in neuron projection; plasma membrane; and synapse. Is expressed in several structures, including adult head; embryonic head epidermis; embryonic head sensory system; gnathal primordium; and labral sensory complex primordium. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See NtR in Genome Data Viewer
    Location:
    58B10-58C1; 2-98 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (22127808..22130184)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (18015313..18017689)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene Verprolin 1 Neighboring gene meiotic from via Salaria 332 Neighboring gene Golgi matrix protein 130 kD Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene arc Neighboring gene gomdanji

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables acetylcholine-gated monoatomic cation-selective channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables extracellular ligand-gated monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transmembrane signaling receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in chemical synaptic transmission IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in monoatomic ion transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in regulation of membrane potential IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of acetylcholine-gated channel complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in neuron projection IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in synapse IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    NtR
    Names
    CG6698-PA
    CG6698-PB
    NtR-PA
    NtR-PB

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      22127808..22130184
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_143701.4NP_651958.2  NtR, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651958.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      H8F4S1, Q9W288
      Related
      FBpp0071676
      Conserved Domains (2) summary
      pfam02931
      Location:212429
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam12248
      Location:90191
      Methyltransf_FA; Farnesoic acid 0-methyl transferase
    2. NM_001259528.2NP_001246457.1  NtR, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001246457.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4K8A6, H8F4S1
      Conserved Domains (2) summary
      pfam02931
      Location:205422
      Neur_chan_LBD; Neurotransmitter-gated ion-channel ligand binding domain
      pfam12248
      Location:90191
      Methyltransf_FA; Farnesoic acid 0-methyl transferase