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    CG30054 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 246420, updated on 9-Dec-2024

    Summary

    Official Symbol
    CG30054provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0050054
    Locus tag
    Dmel_CG30054
    See related
    AllianceGenome:FB:FBgn0050054
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    Dmel\CG30054; Galphaq; GNAQ/11/14; Gqalpha
    Summary
    Predicted to enable G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Predicted to be part of heterotrimeric G-protein complex. Predicted to be active in cytoplasm. Is expressed in photoreceptor neurons. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome; congestive heart failure; and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    NEW
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    Genomic context

    See CG30054 in Genome Data Viewer
    Location:
    49B9-49B9; 2-67 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2R NT_033778.4 (12623726..12625352)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2R NT_033778.3 (8511231..8512857)

    Chromosome 2R - NT_033778.4Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR43909 Neighboring gene Amphiphysin Neighboring gene uncharacterized protein Neighboring gene G protein alpha subunit q Neighboring gene uncharacterized protein Neighboring gene muskelin

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables G protein-coupled receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled receptor binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables G-protein beta/gamma-subunit complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G-protein beta/gamma-subunit complex binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables GTPase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables guanyl nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in adenylate cyclase-modulating G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of heterotrimeric G-protein complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein
    Names
    CG30054-PE
    CG30054-PF

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033778.4 Reference assembly

      Range
      12623726..12625352
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001043073.3NP_001036538.3  uncharacterized protein Dmel_CG30054, isoform E [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036538.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q0E9A7
      Conserved Domains (2) summary
      cd00066
      Location:34347
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
      smart00275
      Location:13351
      G_alpha; G protein alpha subunit
    2. NM_001201985.1NP_001188914.1  uncharacterized protein Dmel_CG30054, isoform F [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001188914.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0B4JD15
      Conserved Domains (2) summary
      cd00066
      Location:12319
      G-alpha; Alpha subunit of G proteins (guanine nucleotide binding)
      smart00275
      Location:12323
      G_alpha; G protein alpha subunit