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    CG42827 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 42763, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42827provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0262009
    Locus tag
    Dmel_CG42827
    See related
    AllianceGenome:FB:FBgn0262009
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG6784; Dmel\CG42827
    Old locus tag
    Dmel_CG6784
    Summary
    Predicted to enable serine-type endopeptidase inhibitor activity. Predicted to be active in extracellular space. Is expressed in testis. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42827 in Genome Data Viewer
    Location:
    94F1-94F1; 3-79 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (23372924..23373600)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (19198646..19199322)

    Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR44322 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. tBRD-1 and tBRD-2 regulate expression of genes necessary for spermatid differentiation. Theofel I, et al. Biol Open, 2017 Apr 15. PMID 28235844, Free PMC Article
    2. tBRD-1 selectively controls gene activity in the Drosophila testis and interacts with two new members of the bromodomain and extra-terminal (BET) family. Theofel I, et al. PLoS One, 2014. PMID 25251222, Free PMC Article
    3. Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation. Grobler Y, et al. PLoS Pathog, 2018 Nov. PMID 30422992, Free PMC Article
    4. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
    5. Transcriptomic analysis of inbreeding depression in cold-sensitive Drosophila melanogaster shows upregulation of the immune response. Vermeulen CJ, et al. J Evol Biol, 2013 Sep. PMID 23944235

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables serine-type endopeptidase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables serine-type endopeptidase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42827-PC
    CG42827-PD

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033777.3 Reference assembly

      Range
      23372924..23373600
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_170073.2 → NP_732863.2  uncharacterized protein Dmel_CG42827, isoform C [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_732863.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V608, Q8IMY9, Q9VCM7
      Conserved Domains (1) summary
      cd00109
      Location:40 → 92
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.

    2. NM_142885.3 → NP_651142.3  uncharacterized protein Dmel_CG42827, isoform D [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_651142.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q4V608, Q8IMY9, Q9VCM7
      Conserved Domains (1) summary
      cd00109
      Location:40 → 92
      KU; BPTI/Kunitz family of serine protease inhibitors; Structure is a disulfide rich alpha+beta fold. BPTI (bovine pancreatic trypsin inhibitor) is an extensively studied model structure.
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q4V608 Q4V608

    Gene LinkOut

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