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    CG42264 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 31504, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG42264provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0259149
    Locus tag
    Dmel_CG42264
    See related
    AllianceGenome:FB:FBgn0259149
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG15768; CG15769; Dmel\CG42264
    Old locus tag
    Dmel_CG15768; Dmel_CG15769
    Summary
    Predicted to enable zinc ion binding activity. Predicted to be involved in proteolysis. Predicted to be active in extracellular space. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG42264 in Genome Data Viewer
    Location:
    5C2-5C2; 1-14 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) X NC_004354.4 (5773023..5776647, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) X NC_004354.3 (5667056..5670680, complement)

    Chromosome X - NC_004354.4Genomic Context describing neighboring genes Neighboring gene MAP kinase activated protein-kinase-2 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-4963 stem loop

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. CRISPR-based modular assembly of a UAS-cDNA/ORF plasmid library for more than 5500 Drosophila genes conserved in humans. Wei P, et al. Genome Res, 2020 Jan. PMID 31722958, Free PMC Article
    2. A genome-wide Drosophila screen for heat nociception identifies α2δ3 as an evolutionarily conserved pain gene. Neely GG, et al. Cell, 2010 Nov 12. PMID 21074052, Free PMC Article
    3. Systematic genetic analysis of muscle morphogenesis and function in Drosophila. Schnorrer F, et al. Nature, 2010 Mar 11. PMID 20220848
    4. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    NOT enables peptidase activity IKR
    Inferred from Key Residues
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG42264-PA
    CG42264-PB

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_004354.4 Reference assembly

      Range
      5773023..5776647 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001258608.1 → NP_001245537.1  uncharacterized protein Dmel_CG42264, isoform B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001245537.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0R934, M9NE86
      Conserved Domains (2) summary
      cd03860
      Location:215 → 520
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
      pfam02244
      Location:144 → 180
      Propep_M14; Carboxypeptidase activation peptide

    2. NM_132032.3 → NP_572260.2  uncharacterized protein Dmel_CG42264, isoform A [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_572260.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0R934, Q9W477
      Conserved Domains (2) summary
      cd03860
      Location:328 → 633
      M14_CP_A-B_like; Peptidase M14 carboxypeptidase subfamily A/B-like
      pfam02244
      Location:241 → 293
      Propep_M14; Carboxypeptidase activation peptide
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NE86 M9NE86
    Q9W477 Q9W477

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